2001
DOI: 10.1076/jcen.23.1.121.1223
|View full text |Cite
|
Sign up to set email alerts
|

Abstract: Depressed individuals show impaired performance in tests of attention and concentration. They also exhibit PET resting state abnormalities in dorsal prefrontal cortex and anterior cingulate, regions known to be substrates of attentional processing in healthy individuals. This chapter outlines a strategy to study neuropsychological mechanisms in emotional disorders using functional imaging methods. It reviews evidence strongly implicating the dorsolateral prefrontal cortex, particularly in the right hemisphere,… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
2
1
1
1

Citation Types

6
133
0
7

Year Published

2004
2004
2020
2020

Publication Types

Select...
6
2
1

Relationship

1
8

Authors

Journals

citations
Cited by 240 publications
(146 citation statements)
references
References 43 publications
6
133
0
7
Order By: Relevance
“…Neuroimaging studies in untreated patients with MDD have repeatedly identified abnormalities of regional cerebral blood flow (rCBF) and glucose metabolism (rCMRglc), most consistently in ventral subdivisions of prefrontal and anterior cingulate (ACC) cortices, but also in other limbic and subcortical regions including hippocampus, amygdala, posterior cingulate, striatum, and thalamus (Drevets, 2000a, b;Liotti and Mayberg, 2001;Seminowicz et al, 2004). Although there is a growing consensus that this network of brain areas is implicated in depression, there is variability in the exact regions reported and in the direction of rCBF and rCMRglc changes.…”
Section: Introductionmentioning
confidence: 99%
“…Neuroimaging studies in untreated patients with MDD have repeatedly identified abnormalities of regional cerebral blood flow (rCBF) and glucose metabolism (rCMRglc), most consistently in ventral subdivisions of prefrontal and anterior cingulate (ACC) cortices, but also in other limbic and subcortical regions including hippocampus, amygdala, posterior cingulate, striatum, and thalamus (Drevets, 2000a, b;Liotti and Mayberg, 2001;Seminowicz et al, 2004). Although there is a growing consensus that this network of brain areas is implicated in depression, there is variability in the exact regions reported and in the direction of rCBF and rCMRglc changes.…”
Section: Introductionmentioning
confidence: 99%
“…Although most depression research has focused on the frontal and anterior cingulate cortex Salvadore et al, 2009;Salvadore et al, 2010), the parietal cortex also has been implicated in emotional deficits (Liotti and Mayberg, 2001;Mayberg, 1997). EEG parietal a asymmetry results have been mixed, but generally point to an increase in leftrelative-to-right a power in depressed patients (Thibodeau et al, 2006).…”
Section: Power Asymmetrymentioning
confidence: 99%
“…Volume reductions have been observed in some studies, but it has been suggested that thalamic volumetric reductions may be more common in bipolar disorder (Strakowski et al). Increased, decreased, and no change of thalamic activity in depressed patients have all been reported (Liotti & Mayberg, 2001). …”
Section: Functional and Structural Anomaliesmentioning
confidence: 99%
“…Decreased bilateral or left prefrontal cortex activation is one of the most often reported functional anomalies in the imaging literature on depression (Davidson et al, 2002). Resting state imaging studies have shown hypometabolism of the frontal lobes, more specifically of the dorsolateral and dorsomedial prefrontal cortex (Davidson et al, 2002;Drevets, 2000;Liotti & Mayberg, 2001). Specificity of reduced activity to the left hemisphere has been replicated numerous times by electroencephalogram (EEG) studies, although negative evidence has also been found (Davidson et al, 2002).…”
Section: Functional and Structural Anomaliesmentioning
confidence: 99%