2021
DOI: 10.1039/d1sc03121j
|View full text |Cite
|
Sign up to set email alerts
|

Abstract: We report a full account of our research on nickel-catalyzed Markovnikov-selective hydroarylation and hydroalkenylation of non-conjugated alkenes, which has yielded a toolkit of methods that proceed under mild conditions with...

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
3
1

Citation Types

0
10
0

Year Published

2021
2021
2024
2024

Publication Types

Select...
8

Relationship

1
7

Authors

Journals

citations
Cited by 19 publications
(10 citation statements)
references
References 68 publications
0
10
0
Order By: Relevance
“…A nickel-catalyzed Markovnikov-selective hydroarylation reaction of non-conjugated alkenes with aryl boronic acid was explored by Engle group (Scheme 14). 33 Alkenyl sulfonamides 21 treated with aryl boronic acid 2 under the conditions of 10 mol% Ni(cod) 2 and 2 equiv. KOH in tert -amyl alcohol at room temperature for 20 h afforded 43–99% yields of products 22 .…”
Section: Intermolecular Hydroarylation Reactionsmentioning
confidence: 99%
“…A nickel-catalyzed Markovnikov-selective hydroarylation reaction of non-conjugated alkenes with aryl boronic acid was explored by Engle group (Scheme 14). 33 Alkenyl sulfonamides 21 treated with aryl boronic acid 2 under the conditions of 10 mol% Ni(cod) 2 and 2 equiv. KOH in tert -amyl alcohol at room temperature for 20 h afforded 43–99% yields of products 22 .…”
Section: Intermolecular Hydroarylation Reactionsmentioning
confidence: 99%
“… 11 Engle reported a directed racemic hydroarylation and hydroalkenylation of unactivated alkenes bearing a remote coordination group. 12 Herein, we report a general protocol to construct tertiary allylic stereogenic centers with two alkyl substituents enabled by Ni-catalysed regio- and enantioselective hydrovinylation of unactivated aliphatic alkenes with vinyl halides ( Scheme 1c ). The strategy allows for the chemoselective hydrofunctionalizations between two alkenes facilitated by a weak coordinating group to furnish substituted tertiary carbon centers with good functional group tolerance.…”
Section: Introductionmentioning
confidence: 99%
“…Hydrometalation of unactivated terminal olefins typically leads to linear product formation. Notably, elegant methods using directing groups have enabled access to favor the branched products from terminal alkenes [12] . Similarly, metal hydride H‐atom transfer (MHAT) strategies have been applied to provide branched selectivity [8j, 13] .…”
Section: Introductionmentioning
confidence: 99%
“…Notably,e legant methods using directing groups have enabled access to favor the branched products from terminal alkenes. [12] Similarly,metal hydride H-atom transfer (MHAT) strategies have been applied to provide branched selectivity. [8j,13] In stark contrast, formation of branched products from activated olefins,s uch as vinylarenes,a re favorably obtained even when using MHATs trategies,a nd only few examples for the formation of linear products have been reported.…”
Section: Introductionmentioning
confidence: 99%