A sandwich-type ECL immunosensor for the sensitive determination of CEA content based on red emission carbon quantum dots as luminophores

Abstract

A sandwich-type electrochemiluminescence (ECL) immunosensor was constructed using red-emitting carbon quantum dots (RCQDs) as luminophores. The RCQDs were prepared in a single step by the simple green microwave synthesis method...

Exogenous Co-Reactant-Free Electrochemiluminescent Biosensor for Ratiometric Measurement of α-Glucosidase Based on a ZIF-67-Regulated Hydrogen-Bonded Organic Framework

“…The resultant gluconic acid can dissolve ZIF-67, leading to an increase in the cathodic ECL signal of HOF-101 and a decrease in the anodic ECL intensity of luminol. This ECL biosensor has distinct advantages: (1) in comparison with single signal-based ECL biosensors, , the ratiometric ECL readout can efficiently avoid a false positive and improve the accuracy; (2) in comparison with H 2 O 2 as an co-reactant, ,, this biosensor possesses good stability and nontoxicity due to the utilization of the dissolved O 2 in aqueous solution as an endogenous co-reactant; (3) ZIF-67 can not only efficiently quench the ECL signal of HOF-101 but also effectively enhance the anodic ECL signal of luminol; and (4) the synthesis conditions of HOF-101 and ZIF-67 are mild and ambient at room temperature without the need of functionalization. This ratiometric ECL biosensor exhibits a broad linear range (0.2–50 U L –1 ) and high sensitivity (a LOD of 0.19 U L –1 ), which are superior to those of the reported α-Glu assays (Table S2).…”

A Novel Electrochemiluminesence Sensor Based on Silver Prussian Blue Analogue/Carboxylated Sulfur‐doped Graphitic Carbon Nitride Nanocomposite for Determination of Lamotrigine

“…Luminophores as one of the most significant components during the light generation processes in ECL can be immobilized at the surface electrode or dissolved in the electrolyte solution. Until now, various compounds such as Si nanocrystals, Ru(bpy) 3 2 + , CdTe, CdSe [21], Ag 2 S [22], luminol [23], iridium complexes, ZnSe, and carbon quantum dots [24] were commonly utilized as ECL luminophore.…”