Recent advances in graphene quantum dot-based optical and electrochemical (bio)analytical sensors

Kalkal, Ashish; Kadian, Sachin; Pradhan, Rangadhar; Manik, Gaurav; Gopinath, P.

doi:10.1039/d1ma00251a

Cited by 54 publications

(14 citation statements)

References 257 publications

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“…GQDs functionalized and conjugated with appropriate proteins and antibodies are commonly employed for biosensing (Fan et al, 2015;Xie et al, 2016;Suvarnaphaet and Pechprasarn, 2017;Mansuriya and Altintas, 2020;Tabish et al, 2021). Few examples from literature include GQD conjugated to antihuman immunoglobulin G antibody (mIgG) for sensing of immunoglobulin (Chen et al, 2018), glutathione functionalized GQD for sensing of ATP (Liu et al, 2013), N-functionalized GQD/Au nanoparticle/neuron-specific enolase antibodies (anti-NSE) bioconjugate for label free detection of small cell lung cancer (Kalkal et al, 2020), folic acid modifies/GQD/Au nanoparticle conjugate for ATP sensing (Zhang et al, 2019). Apart from imaging and sensing, GQDs are also gaining growing interest as photosensitizers for PDT.…”

Section: Graphene Quantum Dotsmentioning

confidence: 99%

Semiconductor quantum dots for photodynamic therapy: Recent advances

Uprety

Abrahamse

2022

Front. Chem.

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Photodynamic therapy is a promising cancer treatment that induces apoptosis as a result of the interactions between light and a photosensitizing drug. Lately, the emergence of biocompatible nanoparticles has revolutionized the prospects of photodynamic therapy (PDT) in clinical trials. Consequently, a lot of research is now being focused on developing non-toxic, biocompatible nanoparticle-based photosensitizers for effective cancer treatments using PDT. In this regard, semiconducting quantum dots have shown encouraging results. Quantum dots are artificial semiconducting nanocrystals with distinct chemical and physical properties. Their optical properties can be fine-tuned by varying their size, which usually ranges from 1 to 10 nm. They present many advantages over conventional photosensitizers, mainly their emission properties can be manipulated within the near IR region as opposed to the visible region by the former. Consequently, low intensity light can be used to penetrate deeper tissues owing to low scattering in the near IR region. Recently, successful reports on imaging and PDT of cancer using carbon (carbon, graphene based) and metallic (Cd based) based quantum dots are promising. This review aims to summarize the development and the status quo of quantum dots for cancer treatment.

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Section: Graphene Quantum Dotsmentioning

confidence: 99%

Semiconductor quantum dots for photodynamic therapy: Recent advances

Uprety

Abrahamse

2022

Front. Chem.

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“…[ 16 , 17 ]. Biosensors are used to detect different analytes, including biomolecules, cancer biomarkers, nucleic acids, blood impedance, cellular cytotoxicity, bacteria, and viruses [ [18] , [19] , [20] , [21] ]. Some of the recently developed biosensing techniques used for COVID-19 detection have been mentioned in Table 1 .…”

Section: Sensors Pocts and 3d Printing Technologymentioning

confidence: 99%

Sensing and 3D printing technologies in personalized healthcare for the management of health crises including the COVID-19 outbreak

Kalkal

Allawadhi

Kumar

et al. 2022

Sensors International

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“…Graphene-based materials have gained great interest since they have features that enable the tunability of their physical, electronic, and mechanical properties [ 69 , 119 ]. For example, the electronic conductivity and catalytic properties of carbon structures are affected greatly by their crystallinity.…”

Section: Applications Of Plal Graphene Nanostructuresmentioning

confidence: 99%

Graphene Nanostructures by Pulsed Laser Ablation in Liquids: A Review

Al-Tuwirqi

2022

Materials

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High-quality graphene has demonstrated remarkable mechanical, thermal, electronic, and optical properties. These features have paved the road for the introduction of graphene into numerous applications such as optoelectronics and energy devices, photodegradation, bioimaging, photodetectors, sensors, and biosensors. Due to this, graphene research has accelerated exponentially, with the aim of reaching a sustainable large-scale production process of high-quality graphene that can produce graphene-based technologies at an industrial scale. There exist numerous routes for graphene fabrication; however, pulsed laser ablation in liquids (PLAL) has emerged as a simple, fast, green, and environmentally friendly method as it does not require the use of toxic chemicals. Moreover, it does not involve the use of expensive vacuum chambers or clean rooms. However, the great advantage of PLAL is its ability to control the size, shape, and structure of the produced nanostructures through the choice of laser parameters and liquid used. Consequently, this review will focus on recent research on the synthesis of graphene nanosheets and graphene quantum dots via PLAL and the effect of experimental parameters such as laser wavelength, pulse width, pulse energy, repetition rate, irradiation time, and liquid media on the produced nanostructures. Moreover, it will discuss extended PLAL techniques which incorporate other methods into PLAL. Finally, different applications that utilize nanostructures produced by PLAL will be highlighted. We hope that this review will provide a useful guide for researchers to further develop the PLAL technique and the fabrication of graphene-based materials.

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Recent advances in graphene quantum dot-based optical and electrochemical (bio)analytical sensors

Abstract: Since the day of its origin, the graphene quantum dots (GQDs) are considered a predominant material for biosensing applications in view of their unique and exciting electronic, physicochemical and optical...

Cited by 54 publications

References 257 publications

Semiconductor quantum dots for photodynamic therapy: Recent advances

Semiconductor quantum dots for photodynamic therapy: Recent advances

Sensing and 3D printing technologies in personalized healthcare for the management of health crises including the COVID-19 outbreak

Graphene Nanostructures by Pulsed Laser Ablation in Liquids: A Review

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