Simultaneous detection of paracetamol and 4-aminophenol at nanomolar levels using biocompatible cysteine-substituted phthalocyanine

Abstract

Extension of the conjugation and biocompatibility of the phthalocyanine molecule is expected to improve its stability and interaction with bio-molecules without any fouling.

Gold Nanoparticles/Mo2C/MoO2-Modified Electrodes for Nucleic Acid Detection through CRISPR/Cas12a Photoelectrochemical Assay

“…The cyclic voltammetry (CV) behavior of p -AP and Ru­(bpy) 3 Cl 2 shows that the redox peak of the p -AP/ p -quinonimine ( p -QI) redox couple appears at about −0.02 to +0.15 V (red curve), whereas the redox peak of the Ru­(bpy) 3 2+ /Ru­(bpy) 3 3+ redox couple appears at about 0.99–1.05 V (blue curve; Figure A). p -AP has a strong oxidation peak at approximately 0.15 V with higher current intensity, whereas Ru­(bpy) 3 2+ indicates an oxidation peak at about 1.05 V with indistinct current intensity. The oxidation potential of p -AP is lower than that of Ru­(bpy) 3 2+ , indicating easier oxidation of p -AP than Ru­(bpy) 3 2+ .…”

Cyclic and Linear Sweep Voltammetric Studies of a Modified Carbon Paste Electrode with Nickel Oxide Nanoparticles toward Tamoxifen: Effects of Surface Modification on Electrode Response Kinetics

“…According to the discussion illustrated above, quantification, detection, and separation of TAM in biological fluids and pharmaceutical formulations have been followed by researchers. For this goal, various analytical techniques including high-performance liquid chromatography (HPLC), gas chromatography (GC), nonaqueous capillary electrophoresis, potentiometry, GC-mass spectrometry, polarography, single sweep voltammetry, and spectrophotometry have been used. − Compared to the mentioned analytical techniques, electrochemical methods are more important to analytical chemists for analyzing various compounds containing electroactive functional groups due to their excellent advantages such as low cost, high sensitivity, and relatively short analysis time. − Accordingly, introducing novel catalysts/compounds with simple/eco-friendly synthesis procedures for various chemical applications has great interest. − Thus, electrochemical methods have adopted great application in detecting and determining various compounds such as pharmaceutics and biomolecules. − Anticancer drugs have OH and NH 2 electroactive functional groups, which can generate electroanalytical signals due to electrooxidation or due to oxidative cyclization reactions . To enhance selectivity, sensitivity, and other characteristics of the electrode, surface modification of electrodes has been used.…”

Nickel Selenide Quantum dot Reactor for Electro‐oxidation of Nevirapine in Wastewater

“…Amongst these techniques, electrochemical methods have attracted the attention of most researchers because of their simplicity, fast response, cost-effectiveness, reliability and reproducibility, enhanced sensitivity and fast alternative to the above-mentioned, mostly expensive and complicated techniques. [4,5,14,15] Modification of the electrode surfaces can improve the analytical performance of sensors due to the provision of enhanced sensitivity, low detection limits, high stability, wide linear range, and high selectivity which cannot be achieved using bare electrodes. [4,16,17] Among the wide range of materials used for electrode modification, nanomaterials have been widely applied in electrochemical sensors.…”