2011
DOI: 10.1039/c0cs00118j
|View full text |Cite
|
Sign up to set email alerts
|

Abstract: Fluorescent probes have been used extensively to monitor biomolecules and biologically relevant species in vitro and in vivo. A new trend in this area that has been stimulated by the desire to obtain more detailed information about the biological effects of analytes is the change from live cell to whole animal fluorescent imaging. Zebrafish has received great attention for live vertebrate imaging due to several noticeable advantages. In this tutorial review, recent advances in live zebrafish imaging using fluo… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
2
1
1

Citation Types

1
108
0

Year Published

2012
2012
2021
2021

Publication Types

Select...
10

Relationship

0
10

Authors

Journals

citations
Cited by 220 publications
(109 citation statements)
references
References 59 publications
1
108
0
Order By: Relevance
“…Numerous applications using zebrafish embryos as a vertebrate model organism involve a vast selection of fluorescent probes like fluorescent proteins, inorganic probes and organic probes [37]. However, the expression of fluorescent proteins requires various manipulations such as RNA or DNA injection and only provides enough signal after several hours of delay depending on the biosynthetic machinery.…”
Section: Study Of the Polymer Probe Internalization And Cytotoxicity mentioning
confidence: 99%
“…Numerous applications using zebrafish embryos as a vertebrate model organism involve a vast selection of fluorescent probes like fluorescent proteins, inorganic probes and organic probes [37]. However, the expression of fluorescent proteins requires various manipulations such as RNA or DNA injection and only provides enough signal after several hours of delay depending on the biosynthetic machinery.…”
Section: Study Of the Polymer Probe Internalization And Cytotoxicity mentioning
confidence: 99%
“…197 Unlike opaque mouse tissue, zebrafish larvae possess minimal light scattering, which allows in vivo imaging even by visible light excitation.…”
Section: In Vivo Zn 2+ Imaging In Small Animal Modesmentioning
confidence: 99%
“…[17] Zebrafish embryos injected with nanosensor 1 into their heart ventricles showed no apparent DOX and UCL signals in the vascular system of the zebrafish (Figure 4 a), which indicated that the anticancer drug DOX cannot be released without NIR exposure. Interestingly, nanosensor 1 showed significantly brightened UCL signals (Figure 4 a and Movie S3) in the zebrafish heart regions when exposed to NIR light for 60 min; these signals resulted from the NIR-triggered drug release, as confirmed by the clearly intensified DOX signal in the zebrafish vessels (Figure 4 a and Movie S4).…”
mentioning
confidence: 94%