Eradication of Anopheles gambiae from Brazil: lessons for malaria control in Africa?

Killeen, Gerry F.; Fillinger, Ulrike; Ibrahim, Kamarulzaman; Gouagna, Louis C.; Knols, Bart G. J.

doi:10.1016/s1473-3099(02)00397-3

Cited by 224 publications

(212 citation statements)

References 94 publications

Supporting

Mentioning

207

Contrasting

Unclassified

Order By: Relevance

“…Mosquito larvae control has a proven record of lowering malaria transmission or even eradication of malaria mosquitoes (Killeen, Fillinger, Kiche, Gouagna, & Knols, 2002). It has been observed that unlike adult mosquitoes, larvae do not change their behavior to avoid control interventions targeted at larval habitats (Killeen, Fillinger, & Knols, 2002).…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Microbial larvicides for mosquito control: Impact of long lasting formulations of Bacillus thuringiensis var. israelensis and Bacillus sphaericus on non‐target organisms in western Kenya highlands

Derua

Kahindi

Mosha

et al. 2018

Ecology and Evolution

View full text Add to dashboard Cite

The microbial larvicides Bacillus thuringiensis var. israelensis and Bacillus sphaericus have been used extensively for mosquito control and have been found to be effective and safe to non‐target organisms cohabiting with mosquito larvae. Recently developed long lasting microbial larvicides (LLML), although evading the previous challenge of short duration of activity, increase the risk of persistence of toxins in the treated larval habitats. This study monitored the impact of LLML FourStar® and LL3 on non‐target organisms cohabiting with mosquito larvae in an operational study to control malaria vectors in western Kenya highlands. A total of 300 larval habitats were selected in three highland villages. The habitats were first monitored for 5 weeks to collect baseline data on non‐target organisms cohabiting with mosquito larvae and then randomized into two treatment arms (respective FourStar® and LL3) and one control arm. Non‐target organisms were sampled weekly for 5 months after treatment to assess the impact of LLML intervention. Before treatment, the mean density of all non‐target organisms combined in the control, LL3 and FourStar® treated habitats was 1.42, 1.39 and 1.49 individuals per habitat per sampling occasion, respectively. Following treatment, this density remained fairly unchanged for 21 weeks at which time it was 1.82, 2.11, and 2.05 for the respective control, LL3 and FourStar® treated habitats. Statistical analysis revealed that LL3 and FourStar® did not significantly alter abundance, richness or diversity of the 11 taxa studied, when comparing the intervention and control larval habitats. However, both FourStar® and LL3 significantly reduced the density of malaria vectors. In conclusion, one round of label rate application of FourStar® or LL3 in natural larval habitats did not alter richness, abundance or diversity of the monitored aquatic non‐target organisms cohabiting with mosquito larvae to an ecologically significant level.

show abstract

Section: Introductionmentioning

confidence: 99%

“…Larviciding with chemical agents has been a historically important component of malaria vector control (Killeen, Fillinger, Kiche, et al., 2002). However, due to significant adverse effects to other non‐target species, chemical larvicides have received gradually less attention in the past decades.…”

Section: Introductionmentioning

confidence: 99%

Microbial larvicides for mosquito control: Impact of long lasting formulations of Bacillus thuringiensis var. israelensis and Bacillus sphaericus on non‐target organisms in western Kenya highlands

Derua

Kahindi

Mosha

et al. 2018

Ecology and Evolution

View full text Add to dashboard Cite

show abstract

“…[9][10][11] While ITNs are currently the priority strategy, there is growing interest in attacking the aquatic stages of malaria vectors with microbial larvicides, in conjunction with environmental management. 5,6,[12][13][14][15][16][17][18][19][20][21] Presently, microbial larvicides are being used in an operational context only in Dar es Salaam, in the United Republic of Tanzania. 22,23 However, in the future larvicide application will be expanded to many of the 15 countries included in the President's Malaria Initiative and this interest is likely to spread to other African countries.…”

Section: Introductionmentioning

confidence: 99%

Integrated malaria vector control with microbial larvicides and insecticide-treated nets in western Kenya: a controlled trial

Fillinger¹,

Ndenga²,

Githeko³

et al. 2009

Bull World Health Org

Self Cite

197

284

View full text Add to dashboard Cite

Objective To assess the contributions of both microbial larvicides and insecticide-treated nets (ITNs) in terms of reducing malaria incidence in an integrated vector management programme in an area moderately endemic for malaria in the western Kenyan highlands. Methods A pre-post, control group design was used. Larval and adult vector populations were surveyed weekly in six separate valley communities. The incidence of Plasmodium infections in children 6 months to 13 years of age was measured during the long and short rainy seasons each year. Baseline data were collected for 17 months, after which Bacillus-based larvicides were applied weekly to aquatic habitats in three of the valleys for another 19 months. At around the same time the larviciding was initiated, ITNs were introduced gradually into all study communities by the National Malaria Control Programme. The effect of larviciding, ITNs and other determinants of malaria risk was assessed by means of generalized estimating equations. Findings The risk of acquiring new parasite infections in children was substantially and independently reduced by ITN use (odds ratio, OR: 0.69; 95% confidence interval, CI: 0.48-0.99) and larvicide application (OR: 0.44; 95% CI: 0.23-0.82), after adjusting for confounders. Conclusion Vector control with microbial larvicides enhanced the malaria control achieved with ITNs alone. Anti-larval measures are a promising complement to ITN distribution in the economically important highland areas and similar transmission settings in Africa.Une traduction en français de ce résumé figure à la fin de l'article. Al final del artículo se facilita una traducción al español. ‫املقالة.‬ ‫لهذه‬ ‫الكامل‬ ‫النص‬ ‫نهاية‬ ‫يف‬ ‫الخالصة‬ ‫لهذه‬ ‫العربية‬ ‫الرتجمة‬

show abstract

“…Although malaria was already endemic in the area, the greater vectorial capacity of this mosquito species, relative to local species, sparked Plasmodium falciparum malaria epidemics costing 16,000 lives (5) before eradication of An. gambiae by an effective, yet costly, control program (6).…”

mentioning

confidence: 99%

Global traffic and disease vector dispersal

Tatem

Hay

Rogers

2006

Proc. Natl. Acad. Sci. U.S.A.

466

366

View full text Add to dashboard Cite

The expansion of global air travel and seaborne trade overcomes geographic barriers to insect disease vectors, enabling them to move great distances in short periods of time. Here we apply a coupled human-environment framework to describe the historical spread of Aedes albopictus, a competent mosquito vector of 22 arboviruses in the laboratory. We contrast this dispersal with the relatively unchanged distribution of Anopheles gambiae and examine possible future movements of this malaria vector. We use a comprehensive database of international ship and aircraft traffic movements, combined with climatic information, to remap the global transportation network in terms of disease vector suitability and accessibility. The expansion of the range of Ae. albopictus proved to be surprisingly predictable using this combination of climate and traffic data. Traffic volumes were more than twice as high on shipping routes running from the historical distribution of Ae. albopictus to ports where it has established in comparison with routes to climatically similar ports where it has yet to invade. In contrast, An. gambiae has rarely spread from Africa, which we suggest is partly due to the low volume of sea traffic from the continent and, until very recently, a European destination for most flights.Aedes albopictus ͉ air travel ͉ Anopheles gambiae ͉ biological invasion ͉ shipping

show abstract

Eradication of Anopheles gambiae from Brazil: lessons for malaria control in Africa?

Cited by 224 publications

References 94 publications

Microbial larvicides for mosquito control: Impact of long lasting formulations of Bacillus thuringiensis var. israelensis and Bacillus sphaericus on non‐target organisms in western Kenya highlands

Microbial larvicides for mosquito control: Impact of long lasting formulations of Bacillus thuringiensis var. israelensis and Bacillus sphaericus on non‐target organisms in western Kenya highlands

Integrated malaria vector control with microbial larvicides and insecticide-treated nets in western Kenya: a controlled trial

Global traffic and disease vector dispersal

Contact Info

Product

Resources

About