Search citation statements

Order By: Relevance

Paper Sections

Select...
2
2
1

Citation Types

13
404
1
7

Year Published

2001
2001
2014
2014

Publication Types

Select...
5
5

Relationship

0
10

Authors

Journals

citations
Cited by 638 publications
(425 citation statements)
references
References 109 publications
13
404
1
7
Order By: Relevance
“…Although aPKC-z showed increased immunoreactivity after Hx and HR, unlike nPKC-y it did not show endothelial cell margin expression, and remained diffusely distributed in the endothelial cell. The PKC isozymes are known to be activated by phosphorylation, and once activated some isozymes translocate from the cytoplasm to the membrane (Ron and Kazanietz, 1999;Gopalakrishna and Jaken, 2000). Phosphorylation of nPKC-y on Thr538 or Ser676 and phosphorylation of aPKC-z on Thr410 is essential for nPKC-y and aPKC-z activation.…”
Section: Discussionmentioning
confidence: 99%
“…Although aPKC-z showed increased immunoreactivity after Hx and HR, unlike nPKC-y it did not show endothelial cell margin expression, and remained diffusely distributed in the endothelial cell. The PKC isozymes are known to be activated by phosphorylation, and once activated some isozymes translocate from the cytoplasm to the membrane (Ron and Kazanietz, 1999;Gopalakrishna and Jaken, 2000). Phosphorylation of nPKC-y on Thr538 or Ser676 and phosphorylation of aPKC-z on Thr410 is essential for nPKC-y and aPKC-z activation.…”
Section: Discussionmentioning
confidence: 99%
“…26 -28 ROI-inducing stimulations, termed oxidative stress, activate cells by phosphorylation of target proteins. 29,30 In contrast, oxidative stress by radiation, anticancer agents and postischemic reperfusions induces cell impairment and apoptosis through peroxidation of proteins and DNA and activation of the molecules in the death-signaling pathways. [31][32][33] Although the details of ROI-associated apoptotic signaling have not been clarified, the finding that ROIs reduce ⌬⌿ m and finally activate caspase-9 and caspase-3 is well known.…”
Section: Discussionmentioning
confidence: 99%
“…PKCs contain several cysteine-rich regions in the regulatory domain and at the catalytic site, which are redox sensitive (202) and therefore potential targets for HNE conjugation. HNE could also potentially modulate PKC activity through forming adducts with lysine or histidine residuals that are essential for enzyme activity.…”
Section: A Activation Of Protein Kinase C By Hnementioning
confidence: 99%