Search citation statements

Order By: Relevance

Paper Sections

Select...
3
1

Citation Types

0
19
0

Year Published

2004
2004
2018
2018

Publication Types

Select...
7
1

Relationship

0
8

Authors

Journals

citations
Cited by 30 publications
(19 citation statements)
references
References 24 publications
0
19
0
Order By: Relevance
“…Our results agree with those of previous studies performed on various other types of cells, which have indicated that IFN␣ and IFN␥ have induced increases in the expression of MHC Class I molecules, although the degree of increase has varied among different cell lines. 17,22,28,33,35 The upregulation of MHC Class I expression in our series followed a dose-dependent response with a different maximal plateau concentration for each cytokine. The S-496 cell line was most responsive to IFN␣ enhancement of MHC molecules, followed by the R-572, D-431, and U87MG cell lines.…”
Section: Discussionmentioning
confidence: 73%
See 2 more Smart Citations
“…Our results agree with those of previous studies performed on various other types of cells, which have indicated that IFN␣ and IFN␥ have induced increases in the expression of MHC Class I molecules, although the degree of increase has varied among different cell lines. 17,22,28,33,35 The upregulation of MHC Class I expression in our series followed a dose-dependent response with a different maximal plateau concentration for each cytokine. The S-496 cell line was most responsive to IFN␣ enhancement of MHC molecules, followed by the R-572, D-431, and U87MG cell lines.…”
Section: Discussionmentioning
confidence: 73%
“…Authors of other studies have also suggested that IFN␥ is a more potent immunomodulator than IFN␣ in several cell types. 28,41,42 On the other hand, Hofbauer, et al, 17 have reported a stronger upregulation of MHC Class I induced by IFN␣ rather than IFN␥ on neoplastic melanomas. In our experiment the S-496 cell line similarly displayed a strong responsiveness to IFN␣, but was not responsive to treatment with IFN␥.…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…IFNa facilitates major histocompatibility complex (MHC) class I expression of cervical epithelial cells, 18 induces a T helper (Th) 1 type of adaptive response, and initiates multiple antiviral mechanisms in neighboring cells. The antiviral effect includes inhibition of HIV-1 replication 19 and may be an effective strategy in limiting the initial viral dissemination beyond the critical lamina propria foci of the CD4 + memory T cells in which most initial replication occurs.…”
Section: Discussionmentioning
confidence: 99%
“…A number of co-stimulatory molecules have been described, with the majority being members of B7 family [107]. With regards to the FRT, MHC II expression has been demonstrated [108,109], but CD80 and CD86 have largely been undetectable [110,111]. However, in previous functional studies in a rat model, we found that antibodies to either CD80 or CD86 inhibit antigen presentation by uterine and vaginal cells suggesting that the antigen presentation was at least partly dependent on the two co-stimulatory molecules [112].…”
Section: Antigen Presentationmentioning
confidence: 99%