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Cited by 24 publications
(21 citation statements)
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References 31 publications
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“…This has led to the suggestion that, as in birds and mammals, local tissue metabolism of TH by deiodinase (dio) enzymes may be a key aspect of salmonid endocrinology [5]. We surveyed the Atlantic salmon genome (NCBI: AGKD030000000) and found six distinct loci encoding dio paralogs.…”
Section: Resultsmentioning
confidence: 99%
“…This has led to the suggestion that, as in birds and mammals, local tissue metabolism of TH by deiodinase (dio) enzymes may be a key aspect of salmonid endocrinology [5]. We surveyed the Atlantic salmon genome (NCBI: AGKD030000000) and found six distinct loci encoding dio paralogs.…”
Section: Resultsmentioning
confidence: 99%
“…We found increased levels of plasma T 4 and T 3 in smolts; however, we did not find higher levels of pituitary thyroid-stimulating hormone (TSH) mRNA by microarray. Although TSH is the primary stimulant of T4 production and release by the thyroid, recent studies in coho salmon (Oncorhynchus kistuch) found that pituitary TSH mRNA levels decrease during smolting, plasma and pituitary TSH do not change, yet plasma thyroid hormones increase (Larsen et al, 2011). Increased circulating thyroid hormones in the absence of large changes in TSH can be explained by an observed increase in thyroid sensitivity to TSH that occurs during smolt development (Specker and Schreck, 1984).…”
Section: Endocrinologymentioning
confidence: 99%
“…Two potential targets are the thyroid axis and the gill Na + , K + ATPase system. Thyroid stimulating hormone (TSH) is the pituitary factor responsible for causing release of thyroid hormone from the thyroid gland and it has been previously demonstrated that TSH mRNA levels increase prior to smolting in coho salmon (Larsen et al 1997). Furthermore, Dickhoff et al (1982 demonstrated that thyroid hormones are elevated in steelhead at the time of smolting.…”
Section: Smoltificationmentioning
confidence: 99%