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Cited by 5 publications
(5 citation statements)
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“…Actually, only few other immune-related genes were upregulated following infection. The latter is in contradiction with our previous results using the same experimental infection model, the same V. anguillarum strain and the same infective dose (43). During the latter study, V. anguillarum highly upregulated the expression of all genes under study (the same gene panel as currently with the exception of hpc and dic) except for cxcr4 and ccr9.…”
Section: Figure 5 |contrasting
confidence: 99%
See 1 more Smart Citation
“…Actually, only few other immune-related genes were upregulated following infection. The latter is in contradiction with our previous results using the same experimental infection model, the same V. anguillarum strain and the same infective dose (43). During the latter study, V. anguillarum highly upregulated the expression of all genes under study (the same gene panel as currently with the exception of hpc and dic) except for cxcr4 and ccr9.…”
Section: Figure 5 |contrasting
confidence: 99%
“…The expression of sensor (tlr3, tlr5m, cxcr4, ccr9), regulatory (il10, cas1, il1β, tnfα, mif1, cxcl8) and effector (hpc, dic) genes was studied early upon infection as the first time points of infection are critical for fish immunity (67). Previously, we demonstrated the expression of all sensor and regulatory genes under study in axenic sea bass larvae (43). The expression of hpc and dic has been demonstrated by others in axenic and non-axenic sea bass larvae, respectively (44,67).…”
Section: Figure 5 |mentioning
confidence: 99%
“…In the first one, after 400 ATUs, Atlantic salmon were vaccinated with IPath ® against the bacterium A. salmonicida. Unlike reported in sea bass larvae exposed to recombinant ferritin and subsequently infected with Vibrio anguillarum [22], IPath ® -vaccinated fish groups showed high activity of MCHII and IL-1β genes in response to A. salmonicida. Among the immune genes associated with fish response to C. rogercresseyi, MHCII and TLR22 genes have been associated with inflammatory responses [62].…”
Section: Discussioncontrasting
confidence: 82%
“…Moreover, the antiviral activity of two isoforms of hepcidin has been reported in turbot [21]. On the other hand, immunosuppression effects have been reported in European sea bass larvae exposed to recombinant ferritin during Vibrio anguillarum infection [22]. Moreover, for terrestrial organisms, recombinant ferritin has been used for ectoparasite control [23].…”
Section: Introductionmentioning
confidence: 99%
“…Negative roles of ferritins in anti-disease were also observed in other fish species. For instance, in sea bass, recombinant ferritin-H function in the immune-suppression reaction of CXCR4, which is detrimental to innate immunity [ 18 ]. In addition to fishes, the ability of ferritin to enhance immune function is widely reported in other species [ 19 , 20 ].…”
Section: Introductionmentioning
confidence: 99%