Abstract:Objective:To identify and quantify the adverse effects associated with the recombinant human
papillomavirus (types 6, 11, 16 and 18) vaccine in adolescents.Data source:Systematic review of randomized clinical trials from PubMed, SciELO and Lilacs
databases. Articles investigating the safety of the vaccine in subjects under 18
years and comparing the recombinant human papillomavirus types 6, 11, 16 and 18
vaccine with a control group were included. Meta-analyses were performed for the
outcomes of pain, erythema… Show more
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