A new musculoskeletal ultrasound scoring system (US10) of the hands and wrist joints for evaluation of early rheumatoid arthritis patients

Luz, Karine Rodrigues da; Pinheiro, Marcelo M.; Petterle, Giovanna S.; Santos, Marco Aurélio Rocha; Fernandes, Ana; Natour, Jamil; Furtado, Rita Nely Vilar

doi:10.1016/j.rbre.2016.07.006

Cited by 11 publications

(15 citation statements)

References 33 publications

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“…Luz et al proposed a novel ultrasound scoring system for hand and wrist joints (US10) and for evaluation of patients with early RA and correlated the US10 with clinical, laboratory, and functional variables. The proposed US10 scoring system proved to be a useful tool for monitoring inflammation and joint damage in early RA [ 31 ].…”

Section: Discussionmentioning

confidence: 99%

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Comparison of the clinical effectiveness of US grading scoring system vs MRI in the diagnosis of early rheumatoid arthritis (RA)

Zhang

et al. 2017

J Orthop Surg Res

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BackgroundAs an irreversible disease, a treatment delay can negatively affect treatment response in rheumatoid arthritis (RA). Ultrasound and MRI have played an important role in assessing disease progression and response to treatment in RA for many years. The present study was designed to compare the diagnostic efficacy of ultrasound grading and MRI in early RA.MethodsIn this retrospective study, 62 early RA patients within 12 months of symptom onset were included. DAS28, rheumatoid factor (RF), CRP, ESR, and anti-cyclic citrullinated peptide antibody (CCP) of the patients were measured. Bilateral hand joints and wrists were examined by ultrasonography (US) and MRI; diagnosis outcome was compared. Relationship between DAS28 scores, laboratory parameters, and ultrasound findings were analyzed.ResultsUltrasound and MRI had an equivalent diagnosis value in synovitis, joint effusion, and tenosynovitis. The detection rate of synovitis, arthroedema, and tenosynovitis on ultrasound and MRI was very close (P > 0.05). The detection rate of bone erosion was lower in ultrasonography than that in MRI (P < 0.05). There were significant differences between power Doppler ultrasonography (PDUS) and gray-scale ultrasonography (GSUS) in the diagnosis of synovitis (χ 2 = 3.92, P < 0.05); the sensitivity of GSUS was better than that of PDUS (P < 0.05). PDUS was positively correlated with DAS28, ESR, CRP, and CCP (P < 0.01), but not correlated with RF and disease duration (P > 0.05). GSUS was positively correlated with RF and CRP (P < 0.01), but not correlated with DAS28, CCP, ESR, and disease duration (P > 0.05). Bone erosion was positively correlated with disease duration, CCP, and RF (P < 0.01) and was not correlated with DAS28, ESR, and CRP (P > 0.05).ConclusionUltrasonography has a high reliability in the diagnosis of early RA in synovitis, joint effusion, tenosynovitis, and bone erosion. Ultrasonography and clinical and laboratory parameters had a great correlativity. Both ultrasound and MRI are effective techniques. In view of the advantages of low cost and convenience, ultrasound may be a better choice during early RA diagnosis.

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Section: Discussionmentioning

confidence: 99%

“…Previously, some simplified ultrasound scoring methods have been reported and analyzed correlatively with clinical manifestations [ 22 ]. But there is a lack of contrast between clinical, laboratory, and radiologic imaging.…”

Section: Introductionmentioning

confidence: 99%

Comparison of the clinical effectiveness of US grading scoring system vs MRI in the diagnosis of early rheumatoid arthritis (RA)

Zhang

et al. 2017

J Orthop Surg Res

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“…The B‐mode scoring system was built upon a previously established scoring system for hemophilia that was modified and expanded. The Doppler scoring system follows other adult and pediatric‐specific scoring systems and definitions . However, these systems were not all developed for or assessed in the pediatric knee with inflammatory arthritis, and most do not include the parapatellar recesses, which provide an important sonographic window for the detection of pathology.…”

Section: Methodsmentioning

confidence: 99%

Novel Ultrasound Image Acquisition Protocol and Scoring System for the Pediatric Knee

Ting

Vega‐Fernandez

Oberle

et al. 2019

Arthritis Care & Research

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“…US displays a remarkable performance in diagnosing inflammatory lesions and assessing structural damage with the development of high-frequency US technology [ 15 , 16 ]. US offers many advantages, such as accessibility, low cost, and lack of irradiation [ 17 ].…”

Section: Discussionmentioning

confidence: 99%

Knee alterations in rheumatoid arthritis: Comparison of US and MRI

2021

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Objective This study was designed to compare the diagnostic efficacy of ultrasonography (US) and magnetic resonance imaging (MRI) in detecting changes in the knee of patients with rheumatoid arthritis (RA) and discover the possible association between the serological index and bone erosion detected by US. Patients and methods In this retrospective study, the US images and MRI findings of the knee in patients with RA from December 2017 to January 2020 were evaluated. Diagnostic outcomes were compared. The rheumatoid factor, C-reactive protein, erythrocyte sedimentation rate, and anti-cyclic citrullinated peptide antibody (ACPA) levels of the patients were recorded. The relation between laboratory index and US findings was analyzed by multivariable logistic regression. Results US showed remarkable accuracy, sensitivity, and specificity in diagnosing synovitis, bone erosion, and soft tissue swelling. In terms of reliability, the agreement between US and MRI was moderate to almost perfect. Meanwhile, a positive association between ACPA level and bone erosion was observed in patients with RA. Conclusions US may have a role as the initial imaging modality in patients with RA. Patients with higher ACPA levels may need more active treatment because they are more likely to have bone erosion detected by US.

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A new musculoskeletal ultrasound scoring system (US10) of the hands and wrist joints for evaluation of early rheumatoid arthritis patients

Abstract: The proposed US10 scoring system proved to be a useful tool for monitoring inflammation and joint damage in early RA patients, demonstrating significant correlations with longitudinal changes in disease activity and functional status.

Cited by 11 publications

References 33 publications

Comparison of the clinical effectiveness of US grading scoring system vs MRI in the diagnosis of early rheumatoid arthritis (RA)

Comparison of the clinical effectiveness of US grading scoring system vs MRI in the diagnosis of early rheumatoid arthritis (RA)

Novel Ultrasound Image Acquisition Protocol and Scoring System for the Pediatric Knee

Knee alterations in rheumatoid arthritis: Comparison of US and MRI

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