Influência das comorbidades na capacidade funcional de pacientes com artrite reumatoide

Marques, Wanessa Vieira; Cruz, Vítor Alves; Rêgo, Jozélia; Silva, Nílzio Antônio da

doi:10.1016/j.rbr.2015.01.009

Cited by 24 publications

(15 citation statements)

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“…It could be explained by some cultural features which may influence disease management in China. Previous studies have reported that gender [10], age [11, 16], SES [12], comorbidities [13, 14], and pinch strength [17, 20] were associated with the HAQ-DI in RA patients. However, our study demonstrated there were no association between these variables and the HAQ-DI.…”

Section: Discussionmentioning

confidence: 99%

“…Developed in 1978, the health assessment questionnaire-disability index (HAQ-DI) remained the gold standard for measuring functional disability in RA [8, 9]. Current epidemiological evidence suggested gender [10], age [11], socioeconomic status (SES) [12], disease duration [11, 12], comorbidities [13, 14], pain [15, 16], disease activity [9, 13], laboratory indexes [17, 18], medication adherence [19], grip strength [17, 20], joints damage [9], anxiety/depression [21, 22], and quality of life [1, 4] were significantly associated with the HAQ-DI in RA patients. Only a study from Finland [20] in RA identified that joint mobility have greatest influence on the HAQ-DI.…”

Section: Introductionmentioning

confidence: 99%

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Functional disability associated with disease and quality-of-life parameters in Chinese patients with rheumatoid arthritis

Zhang

et al. 2017

Health Qual Life Outcomes

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BackgroundAs an important outcome measure among rheumatoid arthritis (RA) patients, functional disability may contribute to unemployment, loss of work productivity, and impaired quality of life. However, little is known about the risk factors of functional disability in Chinese RA patients. This study aimed (1) to examine the prevalence of functional disability in Chinese RA patients; (2) to explore factors associated with the health assessment questionnaire-disability index (HAQ-DI).MethodsA total of 101 RA patients in this cross-sectional study underwent standardized laboratory examinations and responded to the questionnaire for demographic data, the HAQ-DI for functional disability, the Compliance Questionnaire on Rheumatology (CQR) for medication adherence, the Hospital Anxiety and Depression Scale (HADS) for psychological status, and the Short Form 36 health survey (SF-36) for quality of life. Pain, grip/pinch strength, disease activity, and large joint mobility were recorded. Independent samples t-tests, chi-square analyses, and logistic regression modeling were used to analyze the data.ResultsThe mean ± SD age of RA patients was 54.9 ± 11.9 years. Approximately 15.8% RA patients in mainland China experience functional disability (defined as a HAQ-DI score ≥ 1). Long disease duration, pain, high disease activity, a larger number of tender and swollen joints, high C-reactive protein (CRP) level, decreased grip strength, and limitation of shoulder, elbow, wrist, knee, and ankle motion were associated with the HAQ-DI. Participants with functional disability tended to have more severe depressive symptoms and a lower quality of life compared with individuals without functional disability. Stepwise logistic regression analyses found that limitation of wrist extension (P = 0.001) and lower body pain (BP) score (P = 0.001) explained higher HAQ-DI score.ConclusionsThe present study reported that functional disability was common in Chinese RA patients. A low quality of life and limitation of joint mobility had great impacts on functional disability in Chinese RA patients. Targeted and culturally sensitive interventions should be strengthened to delay the onset of disabilities of this population.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Functional disability associated with disease and quality-of-life parameters in Chinese patients with rheumatoid arthritis

Zhang

et al. 2017

Health Qual Life Outcomes

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“…RA occurs in 0.24% to 1% of the population, predominantly among women between the fourth and sixth decades of life [3,4]. According to a multicenter study, the prevalence of RA in Brazil is similar, ranging from 0.2 to 1% of the population [5].…”

Section: Introductionmentioning

confidence: 99%

“…4 Clinical Epidemiology Unit, Heart Institute, University Hospital, School of Medicine, University of São Paulo (Universidade de São Paulo -USP), São Paulo, SP, Brazil. 5 Centro de Referência Policlínica Lindolf Bell, Rua: Dois de Setembro, 1234 -Itoupava Norte, 3°andar, sala 1, Blumenau, SC CEP: 89052-003, Brazil.…”

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confidence: 99%

Staying in the labor force among patients with rheumatoid arthritis and associated factors in Southern Brazil

et al. 2018

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Background: Rheumatoid arthritis primarily affects the working-age population and may cause key functional and work limitations. As the disease progresses, individuals become increasingly unable to conduct daily activities, which has a substantial personal and socioeconomic impact. Fairly recent prior studies showed that patients with RA stop working 20 years earlier than age-matched controls. Factors related to sociodemographic, clinical, care and disease profiles might affect the loss of work capacity. The purpose of this study was to assess the factors associated with the prevalence of working patients with rheumatoid arthritis in the municipality of Blumenau. Methods: A cross-sectional, population-based study was conducted between July 2014 and January 2015, with 296 individuals aged 20 years or older, male and female, living in Blumenau, Santa Catarina state, Brazil, and diagnosed with rheumatoid arthritis according to the 1987 American College of Rheumatology criteria. The prevalence of working patients with RA was assessed by employment status self-reporting during the interview. The chi-squared test, Wald test and Poisson regression analysis were used to test the possible associations between the independent variables and outcome. Results: The prevalence of working patients with rheumatoid arthritis was 44.3%. Patients aged 20 to 59 years had a 90% higher prevalence of outcome than subjects aged 60 years or older. The prevalence of working patients was 132% and 73% higher among individuals with low income and high functional disability, measured using the Health Assessment Questionnaire (HAQ), respectively. Conclusion: The prevalence of working RA patients was highest among adult patients with low income and high functional disability. The first variable is directly related to the individual characteristic, the second reflects the socioeconomic context of the patient, and the third reflects the degree of disability caused by the disease, which may be modifiable by health professionals.

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“…Chronic inf lammatory joint diseases cause constant, prolonged pain that exerts a considerable impact on the lives of affected individuals, rendering them unable to perform day to day tasks 19 . A previous study has identified an association between limited mobility and functional disability in patients with rheumatic disease 20 .…”

Section: Discussionmentioning

confidence: 94%

Disability relating to instrumental activities of daily living in the elderly with rheumatic diseases

Francisco

Marques

Borim

et al. 2018

Rev. bras. geriatr. gerontol.

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Objective: to characterize the sociodemographic profile of elderly persons with arthritis/rheumatism in relation to gender, as well as to estimate the prevalence and factors associated with functional disability for the performance of instrumental activities of daily living (IADL). Method: a cross-sectional population-based study with a sample of 1,136 elderly persons (≥65 years old) from seven Brazilian municipal regions was carried out. Functional capacity was assessed by the self-reports of the elderly in terms of the performance of IADL, using the Lawton Scale. Differences between the genders, according to sociodemographic variables, were verified by the chi-squared test (p<0.05). The prevalence of inability to perform IADL was calculated and the independent associations were verified through multiple logistic regression. Results: the mean age was 72.4 years, 79.1% of the sample were women, and 45.9% of the elderly with arthritis/rheumatism were dependent for the performance of IADL. Differences were observed between the genders in relation to age, marital status, income and household arrangements (p<0.05). A higher prevalence of disability was observed among older elderly persons, those with no schooling and lower incomes, who lived in multigenerational households and who were frail. In the evaluation of the performance of specific activities, elderly persons with arthritis/rheumatism had greater difficulty taking medication (OR: 1,90; CI 95%: 1.19 - 3.06), after adjusting for gender and age. Conclusion: associations were found between functional disability and sociodemographic variables and frailty. Independence in daily activities such as those evaluated in this study is one of the primary conditions for the well-being of the elderly, even in conditions of frailty or chronic diseases.

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Influência das comorbidades na capacidade funcional de pacientes com artrite reumatoide

Abstract: Comorbidities were associated with mobility limitation and functional disability in rheumatoid arthritis patients. The functional comorbidity index proved to be an appropriate comorbidity indicator to determine this association.

Cited by 24 publications

References 37 publications

Functional disability associated with disease and quality-of-life parameters in Chinese patients with rheumatoid arthritis

Functional disability associated with disease and quality-of-life parameters in Chinese patients with rheumatoid arthritis

Staying in the labor force among patients with rheumatoid arthritis and associated factors in Southern Brazil

Disability relating to instrumental activities of daily living in the elderly with rheumatic diseases

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