Diferença na degeneração articular de acordo com o tipo de esporte

Abstract

Objective To determine whether type-II collagen degradation is determined by the type of sport. Carboxy-terminal telepoptide of type-II collagen (CTX-II), a serum biomarker of collagen degradation, was measured in athletes who play different sports, and was compared with matched controls. Methods The sample size consisted of 70 female participants aged between 18 and 25 years, 15 of whom were members of a soccer team, 10 of a futsal (a variant of association football played on a hard court) team, 10 of a handball team, 18 of a volleyball team, and 7 of a swimming team. A total of 9 age- and sex-matched individuals with sedentary lifestyles were included in the control group. 3-mL blood samples were collected from each participant, and they were analyzed using an enzyme-linked immunosorbent assay (ELISA). Results A comparison of the CTX-II concentrations of the players of different sports with those of the control group resulted in the following p -values: volleyball ( p = 0.21); soccer ( p = 0.91); handball ( p = 0.13); futsal ( p = 0.02); and swimming ( p = 0.0015). Therefore, in the investigated population, futsal represented the highest risk for type-II collagen degradation and, consequently, for articular cartilage degradation, whereas swimming was a protective factor for the articular cartilage. No statistically significant difference was found in the body mass index among the groups. Conclusion Futsal players are exposed to greater articular degradation, while swimmers exhibited less cartilage degradation compared with the control group in the study population, suggesting that strengthening the periarticular muscles and aerobic exercise in low-load environments has a positive effect on the articular cartilage.

Avaliação do Biomarcador CTX-II em Pacientes com Ruptura do Ligamento Cruzado Anterior – Estudo Piloto

“…The inclusion criteria were: male gender; age between 18 and 35 years; body mass index (BMI) lower than 30 kg/m 2 ; isolated ACL lesions or absence of knee injuries; and patients who did not practice sports, since some previous studies suggest an increase in the levels of CTX-II after the practice of sports in certain conditions. 20,21 The exclusion criteria were: observadas nessa população com um grupo controle composto por pacientes sem alterações metabólicas no joelho que possam levar à degeneração da cartilagem. Métodos Este é um estudo piloto transversal com dois grupos: pacientes com ruptura do LCA e grupo controle (cada grupo era composto por 10 indivíduos do sexo masculino, com 18 a 35 anos de idade, e índice de massa corporal inferior a 30 kg/m 2 ).…”

“…The inclusion criteria were: male gender; age between 18 and 35 years; body mass index (BMI) lower than 30 kg/m 2 ; isolated ACL lesions or absence of knee injuries; and patients who did not practice sports, since some previous studies suggest an increase in the levels of CTX-II after the practice of sports in certain conditions. 20 21 The exclusion criteria were: female gender; presence of degenerative knee or other joint disease; systemic, autoimmune or infectious diseases; other knee ligament injuries; history of knee surgery; lesions of the meniscus or of the associated cartilage (bone bruises on the magnetic resonance imaging [MRI] scans were not considered cartilage lesions, and were included in the study); any previous ACL surgical treatment; and use of nonsteroidal anti-inflammatory drugs for at least 1 month before the evaluation. With these selection criteria, we tried to make our sample as homogeneous as possible and to obtain the lowest risk to present idiopathic OA or other pathologies such as osteoporosis.…”

“…Os critérios de inclusão foram: sexo masculino; idade entre 18 e 35 anos; índice de massa corporal (IMC) inferior a 30 kg/m 2 ; lesões isoladas do LCA ou ausência de lesões no joelho; e sujeitos não praticantes de esportes, pois alguns estudos prévios sugerem aumento de CTX-II após a atividade física em determinadas condições. 20 21 Os critérios de exclusão foram: sexo feminino; presença de doença degenerativa do joelho ou outra doença articular; doenças sistêmicas, autoimunes ou infecciosas; outras lesões no ligamento do joelho; história de cirurgia no joelho; lesões do menisco ou cartilagem (os casos de hematoma ósseo à ressonância magnética não foram considerados lesões de cartilagem, tendo sido incluídos no estudo); qualquer tratamento cirúrgico prévio do LCA; e uso de anti-inflamatórios não esteroides por pelo menos um mês antes da avaliação. Esses critérios de seleção procuram tornar a amostra o mais homogênea possível, com o menor risco de OA idiopática ou outras patologias, como a osteoporose.…”