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Cited by 13 publications
(3 citation statements)
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“…Nanotechnological maneuvers enhance the crucial cellular and tissue recovery and function and repair. Some of the important nanotechnological front comprises the delivery of nanotechnological devices for targeted cellular stimulation of neuronal cells, delivery of therapeutics, and targeted gene delivery to aid neurogenesis (Singh et al, 2021;Asghari et al, 2021;Krishnan, 2021;Carradori et al, 2017). It also comprises drugs loaded within or on the surface of the nanoparticle to ensure increased bioavailability, less toxicity, accurate targeting, and increased potential (Rakotoarisoa and Angelova, 2018;Pampaloni et al, 2018).…”
Section: Assistance Of Nanotechnology For Neurogenesismentioning
confidence: 99%
“…Nanotechnological maneuvers enhance the crucial cellular and tissue recovery and function and repair. Some of the important nanotechnological front comprises the delivery of nanotechnological devices for targeted cellular stimulation of neuronal cells, delivery of therapeutics, and targeted gene delivery to aid neurogenesis (Singh et al, 2021;Asghari et al, 2021;Krishnan, 2021;Carradori et al, 2017). It also comprises drugs loaded within or on the surface of the nanoparticle to ensure increased bioavailability, less toxicity, accurate targeting, and increased potential (Rakotoarisoa and Angelova, 2018;Pampaloni et al, 2018).…”
Section: Assistance Of Nanotechnology For Neurogenesismentioning
confidence: 99%
“…Marta Tunesi et al proposed a delivery system consisting of a semi-interpenetrating polymer network (semi-IPN) prepared by promoting collagen (COLL) fibrillogenesis in the presence of hyaluronic acid (HA) and loaded with gelatin particles. Researchers loaded the selected COLL-LMW HA composites with Tat-Hsp70 finally conveying neuroprotection in an in vivo model of dopaminergic degeneration [121]. Semiinterpenetrating polymer networks (semi-IPNs) based on collagen and poly(ethylene glycol) (PEG) were also investigated to solve the problem of neurodegenerative disorder [99].…”
Section: Application Of Self-assembled Hydrogels In Brain Damagementioning
confidence: 99%
“…Further, medical expenses for PD were estimated at about $14 billion in 2010 and found to be $8.1 billion higher for the same amount of population without PD. With PD, movement problems like rigidity, slowness, and tremor, along with fatigue, depression, pain, and disease development, and PD responds poorly to medicines with a robust progression of the disease. The intraneuronal feature of aggregated and misfolded α-synuclein (α-syn) fibrils in Lewy bodies and Lewy neurites, and loss of dopaminergic neurons in the substantia nigra pars compacta are important hallmarks of PD pathology . In PD dopaminergic therapy, levodopa ( l -DOPA) and dopamine receptor agonists are generally utilized.…”
Section: Introductionmentioning
confidence: 99%