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Cited by 73 publications
(60 citation statements)
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“…This result supports accumulated evidences of the relation between severity of depression symptoms and overall functioning [7,25]. Table II reveals that change in severity within patients is larger than its change between patients; not much change in standard deviation of severity across time can be noted.…”
Section: Discussionsupporting
confidence: 83%
“…This result supports accumulated evidences of the relation between severity of depression symptoms and overall functioning [7,25]. Table II reveals that change in severity within patients is larger than its change between patients; not much change in standard deviation of severity across time can be noted.…”
Section: Discussionsupporting
confidence: 83%
“…Since the definition of an episode requires a minimum number of symptoms, it is possible in this context to have subsyndromal depression and still technically be in remission, even though residual symptoms would convey an increased risk of relapse [76]. Furthermore, none of these definitions includes role and occupational functioning, which may be impaired after all symptoms have resolved and which indicate continued illness [77]. Some antidepressant trials include quality-of-life measures that are not primary outcomes, and without following patients prior to the onset of depression it is difficult to determine whether the quality of life after treatment returns to its premorbid level.…”
Section: The Potential Pipelinementioning
confidence: 99%
“…alternative reasons for symptoms such as grief, stressful life events or physical illness) as well as inconsistencies in symptom count ranges, diagnostic cut-off scores and correlations between instruments. Symptom severity and degree of functional impairment correlate highly, 127 but in individual cases this may not be the situation and some mildly symptomatic individuals may have marked functional impairment while some people who are severely symptomatic may, at least for a period of time, maintain good function.…”
Section: Identifying and Classifying Severe Depressionmentioning
confidence: 99%