2017
DOI: 10.1016/j.jped.2016.08.006
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Abstract: Cardiac dysfunction by echocardiography and serum ferritin value was significantly associated with unfavorable outcomes in pediatric patients with sepsis.

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Cited by 28 publications
(10 citation statements)
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“…Based on our findings, the median value of serum ferritin level was considerably higher in those who were suffering from cardiac dysfunction (EF < 55%) than their healthy counterparts (EF ≥ 55%) with a mean ± SD of 625.6 ± 214.3 and 490 ± 216.2, respectively (P = 0.029). Also, this is consistent with the study performed by Tonial et al, who reported that the mean serum ferritin level was considerably higher in those suffering from cardiac dysfunction than their healthy counterparts (38).…”
Section: Discussionsupporting
confidence: 93%
“…Based on our findings, the median value of serum ferritin level was considerably higher in those who were suffering from cardiac dysfunction (EF < 55%) than their healthy counterparts (EF ≥ 55%) with a mean ± SD of 625.6 ± 214.3 and 490 ± 216.2, respectively (P = 0.029). Also, this is consistent with the study performed by Tonial et al, who reported that the mean serum ferritin level was considerably higher in those suffering from cardiac dysfunction than their healthy counterparts (38).…”
Section: Discussionsupporting
confidence: 93%
“…In a series of recent publications, high levels of serum ferritin at the time of sepsis's diagnosis were associated with an unfavorable outcome. This has been reported particularly in pediatric patients from 28 days to 18 years old [132][133][134]. Although hyperferritinemia has been increasingly acknowledged as a marker of critical illness, neither the reasons for increased ferritinemia nor the consequences of this for disease outcome are known.…”
Section: Sepsismentioning
confidence: 99%
“…The authors also observed a proportionate increase in mortality with rising SF levels. 13 Nevertheless, some of these studies may suffer from an inherent selection bias due to their retrospective study design. This study is the first to explore the prevalence and utility of SF in AES.…”
Section: Discussionmentioning
confidence: 99%
“…9 There is a growing body of research focused on serum ferritin (SF) and its potential role in sepsis, septic shock, and tropical infections. 10 11 12 13…”
Section: Introductionmentioning
confidence: 99%