Diametral compression behavior of biomedical titanium scaffolds with open, interconnected pores prepared with the space holder method

Arifvianto, Budi; Leeflang, M.A.; Zhou, Jie

doi:10.1016/j.jmbbm.2017.01.046

Cited by 20 publications

(11 citation statements)

References 61 publications

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“…The porous titanium scaffold made by 3-D printing technology has good biomechanical properties and biocompatibility compared to titanium and its alloys. Compared to the space-holder technology [37], foaming method [38] and other methods, 3-D printing technology can better control of the porosity, pore diameter, pore volume, spatial arrangement and other surface properties of scaffolds. For treating bone defects in the revision of TKA, the 3-D printed porous titanium scaffold can provide a potentially effective clinical solution that is worthy of further exploration.…”

Section: Results and Analyses Of Cylindrical Modelmentioning

confidence: 99%

Design and Analysis of Three-Dimensional Printing of A Porous Titanium Scaffold

Yang

Yang²,

Shi³

et al. 2021

Preprint

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Objective To develop suitable structural designs for the three-dimensional (3-D) printing of a porous titanium scaffold to fill bone defects in knee joints. Pore diameter and mechanic strength are key factors for the 3-D printing of porous titanium scaffolds. Methods Fifteen different pore unit structural models of titanium scaffolds were designed with 3-D printing computer software; five different scaffold shapes were designed: imitation diamond-60°, imitation diamond-90°, imitation diamond-120°, regular tetrahedron and regular hexahedron. Each structural shape was evaluated with three pore diameters 400μm, 600μm and 800μm, and fifteen types of cylindrical models(diameter: 20mm; height: 20mm). Autodesk Inventor software was used determine the strength and safety of the models by simulating simple strength acting on the knee joints. We analyzed the data and found suitable models for 3-D printing of porous titanium scaffolds. Results Fifteen different types of pore unit structural models were evaluated under positive pressure; the compressive strength was lower when the pore diameter(400μm, 600μm and 800μm) was larger, except for the regular tetrahedron structure. Under lateral pressure, the compressive strength was also lower when the pore diameter(400μm, 600μm and 800μm) was larger. Under torsional pressure, the strength of the imitation diamond structure was similar when the pore diameter(400μm, 600μm and 800μm) was larger, and the strengths of the regular tetrahedron and regular hexahedron structures were lower when the pore diameter(400μm, 600μm and 800μm) was larger. In each case, the compressive strength of the regular hexahedron structure was highest, that of the regular tetrahedron was second highest, and that of the imitation diamond structure was relatively low. Fifteen types of cylindrical models under a set force were evaluated, and the sequence of comprehensive compressive strength, from strong to weak was: regular hexahedron> regular tetrahedron> imitation diamond-120°> imitation diamond-90°> imitation diamond-60°. The compressive strength of cylinder models was higher when the pore diameter was smaller. Conclusion The compressive strength differed among titanium scaffolds with different pore structures. The pore diameter and shapes of the pore structure were important factors influencing the compressive strength. The models of regular hexahedron, regular tetrahedron and imitation diamond-120°appeared to meet the conditions of large pore diameters and high compressive strength. The strength of each structure was lower when the pore diameter(400μm, 600μm and 800μm) was larger.

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Section: Results and Analyses Of Cylindrical Modelmentioning

confidence: 99%

Design and Analysis of Three-Dimensional Printing of A Porous Titanium Scaffold

Yang

Yang²,

Shi³

et al. 2021

Preprint

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“…Ti6Al4V has good heat resistance, strength, plasticity, toughness, formability, corrosion resistance and biocompatibility. Compared to the space-holder technology [ 36 ], oaming method [ 37 ], and other methods, 3D printing technology can better control of the porosity, larger pore size [ 38 ], pore volume, spatial arrangement and other surface properties of scaffolds. The porous titanium scaffold made by 3D printing technology has good biomechanical properties, biocompatibility and lower elastic modulus [ 39 ] compared to titanium and its alloys.…”

Section: Discussionmentioning

confidence: 99%

Design and analysis of three-dimensional printing of a porous titanium scaffold

Yang

Shi

et al. 2021

BMC Musculoskelet Disord

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Objective Mechanic strength, pore morphology and size are key factors for the three-dimensional (3D) printing of porous titanium scaffolds, therefore, developing optimal structure for the 3D printed titanium scaffold to fill bone defects in knee joints is instructive and important. Methods Structural models of titanium scaffolds with fifteen different pore unit were designed with 3D printing computer software; five different scaffold shapes were designed: imitation diamond-60°, imitation diamond-90°, imitation diamond-120°, regular tetrahedron and regular hexahedron. Each structural shape was evaluated with three pore sizes (400, 600 and 800 μm), and fifteen types of cylindrical models (size: 20 mm; height: 20 mm). Autodesk Inventor software was used to determine the strength and safety of the models by simulating simple strength acting on the knee joints. We analyzed the data and found suitable models for the design of 3D printing of porous titanium scaffolds. Results Fifteen different types of pore unit structural models were evaluated under positive pressure and lateral pressure; the compressive strength reduced when the pore size increased. Under torsional pressure, the strengths of the imitation diamond structure were similar when the pore size increased, and the strengths of the regular tetrahedron and regular hexahedron structures reduced when the pore size increased. In each case, the compressive strength of the regular hexahedron structure was highest, that of the regular tetrahedron was second highest, and that of the imitation diamond structure was relatively low. Fifteen types of cylindrical models under a set force were evaluated, and the sequence of comprehensive compressive strength, from strong to weak was: regular hexahedron > regular tetrahedron > imitation diamond-120° > imitation diamond-90° > imitation diamond-60°. The compressive strength of cylinder models was higher when the pore size was smaller. Conclusion The pore size and pore morphology were important factors influencing the compressive strength. The strength of each structure reduced when the pore size (400, 600 and 800 μm) increased. The models of regular hexahedron, regular tetrahedron and imitation diamond-120°appeared to meet the conditions of large pore sizes and high compressive strength.

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“…The porosity and pore size are dependent on the kind of space holder and the ratio of the titanium biomaterial to a space holder. As the space holders, NaCl [80][81][82], sugar crystals [83][84][85], polypropylene carbonate [86], magnesium powder [87,88], carbonates [89][90][91][92], carbamide [93,94], and Mo wire [95] were used. The titanium hydride, which could decompose at elevated temperature, was also applied in powder metallurgy.…”

Section: Pore Shapementioning

confidence: 99%

Structural and Material Determinants Influencing the Behavior of Porous Ti and Its Alloys Made by Additive Manufacturing Techniques for Biomedical Applications

Dziaduszewska

Zieliński

2021

Materials

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One of the biggest challenges in tissue engineering is the manufacturing of porous structures that are customized in size and shape and that mimic natural bone structure. Additive manufacturing is known as a sufficient method to produce 3D porous structures used as bone substitutes in large segmental bone defects. The literature indicates that the mechanical and biological properties of scaffolds highly depend on geometrical features of structure (pore size, pore shape, porosity), surface morphology, and chemistry. The objective of this review is to present the latest advances and trends in the development of titanium scaffolds concerning the relationships between applied materials, manufacturing methods, and interior architecture determined by porosity, pore shape, and size, and the mechanical, biological, chemical, and physical properties. Such a review is assumed to show the real achievements and, on the other side, shortages in so far research.

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Diametral compression behavior of biomedical titanium scaffolds with open, interconnected pores prepared with the space holder method

Cited by 20 publications

References 61 publications

Design and Analysis of Three-Dimensional Printing of A Porous Titanium Scaffold

Design and Analysis of Three-Dimensional Printing of A Porous Titanium Scaffold

Design and analysis of three-dimensional printing of a porous titanium scaffold

Structural and Material Determinants Influencing the Behavior of Porous Ti and Its Alloys Made by Additive Manufacturing Techniques for Biomedical Applications

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