Global analysis of transcriptome sequences highlights accelerated evolution of immune genes in Danio choprae and Danio albolineatus

Bao, Lingsheng; Xia, Jin-lan

doi:10.1016/j.fsi.2017.05.011

Cited by 3 publications

(2 citation statements)

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“…It also plays an important role in detoxification (Shigeyuki et al, 2006). Interestingly, CYP1A1 and CYP17A1 previously reported in D. albolineatus (Bao and Xia, 2017) are both related to Cytochrome P450, arranged by substrate type pathway. UACA has been considered to be a potential target autoantigen in Vogt-Koyanagi-Harada, Behçet's disease, and sarcoidosis, consequently leading to panuveitis (Yamada et al, 2001).…”

Section: Discussionmentioning

confidence: 90%

“…Global analysis of transcriptome sequences in Aldrovandia affinis , a deep-sea fish, has identified a set of genes related to cytoskeletal structures, which means that DNA repair and treatment of genetic information can contribute to adaptation in the deep-sea environment ( Lan et al, 2018 ). Transcriptome analysis in Danio albolineatus and Danio choprae has highlighted the accelerated evolution of immune genes, such as MPG , GTF2E1 , REL , and STAT6 in D. choprae and MYCN , ADORA2A , and CYP17A1 in D. albolineatus ( Bao and Xia, 2017 ). These studies stressed that these naturally selected genes were usually related to immunity and resistance in fish.…”

Section: Introductionmentioning

confidence: 99%

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Analysis of Natural Selection of Immune Genes in Spinibarbus caldwelli by Transcriptome Sequencing

et al. 2020

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Spinibarbus caldwelli is an omnivorous cyprinid fish that is distributed widely in China. To investigate the adaptive evolution of S. caldwelli, the muscle transcriptome was sequenced by Illumina HiSeq 4000 platform. A total of 80,447,367 reads were generated by next-generation sequencing. Also, 211,386 unigenes were obtained by de novo assembly. Additionally, we calculated that the divergence time between S. caldwelli and Sinocyclocheilus grahami is 23.14 million years ago (Mya). And both of them diverged from Ctenopharyngodon idellus 46.95 Mya. Furthermore, 38 positive genes were identified by calculating Ka/Ks ratios from 9225 orthologs. Among them, several immune-related genes were identified as positively selected, such as POLR3B, PIK3C3, TOPORS, FASTKD3, CYPLP1A1, and UACA. Our results throw light on the nature of the natural selection of S. caldwelli and contribute to future immunological and transcriptome studies.

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Section: Discussionmentioning

confidence: 90%

Section: Introductionmentioning

confidence: 99%