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Cited by 64 publications
(48 citation statements)
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References 29 publications
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“…These preliminary data suggest that electrical stimulation of the posterior pharyngeal wall may invoke short-term changes in cortical or subcortical sensorimotor swallowing pathways and supports observations made previously [2,3,9,13]. Several neural mechanisms could be responsible for the post-stimulation changes observed in some of the swallowing variables.…”
Section: Discussionsupporting
confidence: 71%
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“…These preliminary data suggest that electrical stimulation of the posterior pharyngeal wall may invoke short-term changes in cortical or subcortical sensorimotor swallowing pathways and supports observations made previously [2,3,9,13]. Several neural mechanisms could be responsible for the post-stimulation changes observed in some of the swallowing variables.…”
Section: Discussionsupporting
confidence: 71%
“…The hypothesis based on previous studies of dysphagia following stroke was that MEP amplitude would increase by about 60% following a 10 min treatment of 5 Hz stimulation and this would be correlated with positive changes in swallowing function [2,3,9]. Changes in two of three participants (e.g., S1, S3) were consistent with this hypothesis.…”
Section: Discussionsupporting
confidence: 70%
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“…Once oral transfer begins, multiple cortical and subcortical regions of activation have been recorded using fMRI [12,[17][18][19][20][21][22], positron emission tomography (PET) [23][24][25], and MRCP [26][27][28][29][30]. Of these, fMRI provides the most accessible noninvasive procedure to accurately identify functional anatomic networks (see [31] for a review of fMRI benefits and limitations).…”
Section: Ingestion: Oral-stage Anatomymentioning
confidence: 99%
“…7 Intraluminal pharyngeal electrical stimulation (PES) is one such neurostimulation technique that has been shown to promote this type of plasticity in healthy individuals and achieve measurable improvements in swallowing function in dysphagic stroke patients in studies spanning more than a decade. [8][9][10][11][12] In contrast to behavioral swallowing treatments, PES appears to promote functional benefit through a central nonbiomechanical mechanism, such that dysphagia is improved regardless of physiological deficit. Furthermore, the optimal stimulation parameters (5-Hz frequency, 10 minutes duration, and 75% of maximum tolerated intensity) 8 have been shown to reverse the neurophysiological and behavioral effects of experimental brain 1 University of Manchester, Salford, UK 2 Salford Royal Foundation Trust, Salford, UK lesions, 9,13 and a dose-response study provided an optimal regimen in dysphagic stroke patients-once-daily stimulation for 3 days.…”
Section: Introductionmentioning
confidence: 99%