Changes in plasma thyroid hormones and cortisol levels in crucian carp (Carassius auratus) exposed to the extracted microcystins

Li, Dapeng; Xie, Ping; Zhang, Xuezhen

doi:10.1016/j.chemosphere.2008.09.065

Cited by 55 publications

(37 citation statements)

References 44 publications

(54 reference statements)

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“…Treated group exposed to toxic Microcystis showed higher concentrations of Thyroxin hormone levels than control group, indicating increased metabolic activity causing decreased fish performance. This result disagreed with Li et al (2008) and Brar et al (2010) who found that injection of microcystin decreases the thyroid hormones levels in plasma and. Such differences in T3 and T3/T4 ratio may point to environment-related alterations in the peripheral conversion of T4 into T3.…”

Section: Discussioncontrasting

confidence: 55%

Effect of freshwater toxic and non toxic cyanobacteria, (Microcystis aeruginosa) strains on some biochemical parameters of Oreochromis niloticus

Marzouk

Mostafa

Ibrahim

et al. 2013

Egypt. J. of Aquatic Biolo. and Fish.

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Thirty six all male Oreochromis niloticus were divided into two groups, using six glass aquaria. The treated group was fed on a toxic strain of M. aeruginosa, while the control group was fed on a non toxic strain of M. aeruginosa, in order to measure their grazing rates from both strains of M. aeruginosa and consequently its effect on general fish health represented by, clinical signs, hematological changes and biochemical parameters. Grazing rates and daily intake of M. aeruginosa showed close grazing rates between the treated and the control groups with slightly higher intake of non toxic strain than the toxic one were the individual intake was 63,050 and 62,567 cell/ml/fish respectively. Clinical signs in O. niloticus associated with exposure to toxic cyanobacteria were investigated. The observed clinical signs were sluggish movement and reduced reflexes during the late stages of exposure period. Plasma glucose, cortisol, T4, creatinine and AST showed higher concentrations in the treated group than that in the control, indicating on increased fish stress that was reflected in its health state and consequently its performance. On the opposite side, plasma total protein concentration was higher in the control than that in treated group. The hematocrit, plasma albumin, LDH and Alkaline phosphatase concentrations did not show any significant difference in both groups. The study concluded that the uptake of toxic strain of M. aeruginosa via oral route had deleterious effects on some clinical and biochemical parameters of the blood of Nile tilapia which led finally affected the fish health. The study recommendations include prevention and monitoring of organic and inorganic pollution that promote the harmful algal blooms, and take the early preventive measures to avoid toxic effects of cyanobacteria on fish and consequently on humans.

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Section: Discussioncontrasting

confidence: 55%

Effect of freshwater toxic and non toxic cyanobacteria, (Microcystis aeruginosa) strains on some biochemical parameters of Oreochromis niloticus

Marzouk

Mostafa

Ibrahim

et al. 2013

Egypt. J. of Aquatic Biolo. and Fish.

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“…As mentioned above, the endocrine system is very complex and affected by many factors, and previous studies have shown that liver damage may not only induce sex hormone changes [127], but also reduce hepatic thyroxine deiodination in animals [137], which in turn causes a decline in peripheral triiodothyronine production [130]. A previous study demonstrated that chemical-caused effects on one endocrine axis pathway will also indirectly affect the other endocrine axes in zebrafish [138].…”

Section: Sex Hormones Hpg Axis Liver and Endocrine-disrupting Effectsmentioning

confidence: 99%

“…Besides modulating the HPG axis, it has also been previously demonstrated that MCs alter the metabolism of cortisol and thyroid hormone, through activating the hypothalamic-pituitary-adrenal/interrenal (for fish) (HPA/HPI) and hypothalamic-pituitary-thyroid (HPT) axis [130][131][132][133][134][135][136]. As mentioned above, the endocrine system is very complex and affected by many factors, and previous studies have shown that liver damage may not only induce sex hormone changes [127], but also reduce hepatic thyroxine deiodination in animals [137], which in turn causes a decline in peripheral triiodothyronine production [130].…”

Section: Sex Hormones Hpg Axis Liver and Endocrine-disrupting Effectsmentioning

confidence: 99%

A review of reproductive toxicity of microcystins

Chen

Zhang

et al. 2016

Journal of Hazardous Materials

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283

107

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“…High stocking density has been considered as aquaculture related chronic stressor which causes growth suppression (Barton, 1991;Barton & Iwama, 1991;Wedemeyer, 1997). Reasons of this growth suppression might be deteriorating water quality, abnormal social behavior such as social hierarchy, reduced food consumption and altered metabolic and hematological conditions (Papoutsoglou et al, 2006;Li, Xie, & Zhang, 2008;Lupatsch et al, 2010;Tolussi, Hilsdorf, Canneppele, & Moreira, 2010;Faggio, Fedele, Arfuso, Panzera, & Fazio, 2014;Fazio et al, 2015).…”

Section: Introductionmentioning

confidence: 99%

Untitled

Fatima¹,

Izhar²,

Usman³

et al. 2018

Turk. J. Fish. Aquat. Sci.

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High stocking density is a major problem in extensive aquaculture in Pakistan. Present study investigated its effect of growth, levels of thyroxine (T4) and cortisol in two major carps of Pakistan; labeo (Labeo rohita) and catla (Catla catla). One cohort of labeo (n=30) was kept at high stocking density (HD) (25 g/L). HD cohort was split into two replicates, each containing a total of 15 fish. Second cohort of labeo (n=10) was reared at low stocking density (LD) of 4.4 g/L. LD cohort was divided into two replicates, each containing a total of five fish. Similar protocol was followed for catla. Trial continued for the period of 30 days. At the end of trial, condition factor significantly decreased in HD cohorts of both species. Levels of cortisol in HD cohorts (210±2.00 nmol/L in Catla catla; 425±3.00 nmol/L in Labeo rohita) were significantly higher than those in LD cohorts of both species. Values of T4 in HD cohorts were found to be 1.48±0.20 pmol/L in Catla catla and 1.74±0.10 pmol/L in Labeo rohita at the end of trial which were significantly lower than at the commencement of trial. Suppression of growth, elevation in the levels of cortisol and decrease in profile of T4 in HD cohorts of both species was due to stress induced by high stocking density. Furthermore, present study found that optimum stocking density for extensive farming of both species should be approximately 4.4 g/L.

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Changes in plasma thyroid hormones and cortisol levels in crucian carp (Carassius auratus) exposed to the extracted microcystins

Cited by 55 publications

References 44 publications

Effect of freshwater toxic and non toxic cyanobacteria, (Microcystis aeruginosa) strains on some biochemical parameters of Oreochromis niloticus

Effect of freshwater toxic and non toxic cyanobacteria, (Microcystis aeruginosa) strains on some biochemical parameters of Oreochromis niloticus

A review of reproductive toxicity of microcystins

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