Graphene substrates promote adherence of human osteoblasts and mesenchymal stromal cells

Graphene and graphene oxide as nanomaterials for medicine and biology application

“…Cell lines grown in the presence of graphene show higher rate of proliferation, growth and differentiation [93] in comparison to the SiO substrate [6,94,95]. It has been reported that the use of different GO materials for cell cultures of lung epithelium have no impact on the viability and biological response of the cell [96][97][98].…”

“…Graphene/chitosan films demonstrated promising application to enhance and repair tissue functions in tissue engineering [100]. CVD-developed graphene substrate has also proved to be biocompatible for hMSCs and also for human osteoblasts with a higher rate of expansion of cell and stimulating the development and differentiation of cells [94]. Multilayered GO nanosheet assembled by layerby-layer technique can improve the mechanical properties of polyelectrolyte multilayer films for better attachment of cells [101].…”

Synthesis and Biomedical Applications of Graphene: Present and Future Trends

“…Regarding their cell culture studies, an improvement of the osteogenic potential has been achieved using graphene-coated surfaces for the differentiation of human mesenchymal stem cells (hMSCs) and preosteoblasts into osteoblasts [95,96]. Cell culture studies of graphene oxide sheets also show promise as the suitable implant material [97].…”

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“…In addition, graphene is a highly stable material and this characteristic enables its use for various purposes, from electronics to medical treatments (Kalbacova et al 2010). Graphene also has high transparency such that a single-layer graphene absorbs only 2% of visible light; this optical transparency is suitable for photonic and optoelectronic materials (Avouris & Freitag 2014;Zhao et al 2014)self-limiting growth of AB-stacked bilayer graphene (BLG.…”