Antimicrobial (including antimollicutes), antioxidant and anticholinesterase activities of Brazilian and Spanish marine organisms – evaluation of extracts and pure compounds

Bianco, Éverson Miguel; Krug, Jéssica Lenita; Zimath, Priscila Laiz; Kroger, Aline; Paganelli, Camila Jeriane; Boeder, Ariela Maína; Santos, Larissa dos; Tenfen, Adrielli; Ribeiro, Suzi Meneses; Kuroshima, Kátia Naomi; Alberton, Michele Debiasi; Córdova, Caio Maurício Mendes de; Rebelo, Ricardo Andrade

doi:10.1016/j.bjp.2015.07.018

Cited by 19 publications

(13 citation statements)

References 42 publications

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“…The negative results observed for D. anchorata on all strains were expected, extracts having previously had no antimicrobial effect on S. aureus, E. coli, and P. aeruginosa. [21]. D. anchorata served in this study as a negative control, and our results confirm those previously obtained.…”

Section: : Inhibition Diameter (Mm) Of the Aqueous And Ethanoic Extrasupporting

confidence: 92%

Screening of the antimicrobial activity of marine sponge extracts from Martinique

Piron

Pastour

Tysklind

et al. 2021

Preprint

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Marine sponges are known for their antimicrobial, antifungal, and cytotoxic activity. In this study, the activity of aqueous and ethanoic extracts of 3 sponges from Martinique were tested on 5 bacterial strains: Bascillus cereus (CIP 783), Echerichia coli (CIP 54127), Pseudomonas aeruginosa (CIP A22), Staphylococcus aureus (CIP 67.8) and Staphylococcus saprophyticus (CIP 76125). The antimicrobial activity of Agelas clathrodes , Desmapsamma anchorata, and Verongula rigida , was demonstrated using the disc diffusion method and by determining the minimum inhibitory concentration and the minimum bactericidal concentration. The ethanoic extract of Agelas clathrodes had an inhibitory activity specifically on Staphylococcus aureus and Staphylococcus saprophyticus . No activity was observed for the other extracts. Further chemical analyses will be carried out in order to identify the active molecules of these sponges.

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Section: : Inhibition Diameter (Mm) Of the Aqueous And Ethanoic Extrasupporting

confidence: 92%

Screening of the antimicrobial activity of marine sponge extracts from Martinique

Piron

Pastour

Tysklind

et al. 2021

Preprint

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“…Accordingly, L. inermis extract was shown to have bactericidal effects against E. coli ATCC 25922, P. aeruginosa ATCC27853, E. coli isolate, K. pneumonia isolate, S. aureus isolate and Streptococcus pyogenes isolate; but bacteriostatic activity against S. aureus ATCC 25923, MRSA ATCC® 43300TM, P. aeruginosa ATCC27853, K. pneumonia ATCC700603, P. aeruginosa isolate and S. algae isolate. Generally, the activity is considered to be high when MIC is less than10 μg/mL, moderate when MIC is between 10 and100 μg/mL and low when MIC is greater than 100 μg/m [ 33 ].…”

Section: Discussionmentioning

confidence: 99%

Antibacterial activity of methanol extracts of the leaves of three medicinal plants against selected bacteria isolated from wounds of lymphoedema patients

Nigussie

Davey

Legesse

et al. 2021

BMC Complement Med Ther

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Background Patients with lymphoedema are at high risk of getting bacterial and fungal wound infections leading to acute inflammatory episodes associated with cellulitis and erysipelas. In Ethiopia, wound infections are traditionally treated with medicinal plants. Methods Agar well diffusion and colorimetric microdilution methods were used to determine the antibacterial activity of methanol extracts of the three medicinal plants against Staphylococcus aureus, Streptococcus pyogenes, Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, Shewanella alage, methicillin-resistant S. aureus ATCC®43300TM, Staphylococcus aureus ATCC25923, Escherichia coli ATCC25922, Klebsiella pneumoniae ATCC700603, and Pseudomonas aeruginosa ATCC37853. Results The methanol extract of L. inermis leaves showed high activity against all tested bacterial species, which was comparable to the standard drugs. Similarly, the extracts of A. indica showed activity against all tested species though at higher concentrations, and higher activity was recorded against Streptococcus pyogenes isolates at all concentrations. However, the extract of A. aspera showed the lowest activity against all tested species except Streptococcus pyogenes isolates. The lowest minimum inhibitory concentration (MIC) was recorded with the extract of L. inermis against E. coli isolate and S. aureus ATCC 25923. Conclusion Methanol extracts of L. inermis, A. indica, and A. aspera leaves exhibited antimicrobial activity against selected bacterial isolates involved in wound infections, of which the methanol extracts of L. inermis exhibited the highest activity. The results of the present study support the traditional use of plants against microbial infections, which could potentially be exploited for the treatment of wound infections associated with lymphoedema.

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“…The beach-cast seaweeds are considered unusable waste materials, our results of 1/EC 50 show that the extracts analyzed have similar or better antioxidant activity than the reported by Zubia et al (2007) and Bianco et al (2015) for some attached macroalgae species. Also, the antioxidant activity from methanolic and aqueous extracts of the beach-cast seaweeds showed values of 1/EC 50 close to those reported for the commercial standards α-tocopherol and BHT described by Zubia et al (2007).…”

Section: Discussionsupporting

confidence: 50%

“…In recent years, marine macroalgae have attracted attention around the world in the search for bioactive substances to develop new drugs and functional bioproducts due to their low toxicity and high bioactivity (Gullón et al, 2020). As fundamental components of the marine ecosystem, macroalgae constitute one of the most diverse groups among photosynthetic organisms (Bianco et al, 2015), representing a strategic natural resource for biotechnological development. In Brazil, special attention has increased considerably due to its large coastline and wide biodiversity.…”

Section: Introductionmentioning

confidence: 99%

Caracterização química, potencial antioxidante e atividade biológica de macroalgas arribadas do litoral brasileiro

Harb¹

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A wide variety of metabolites extracted from macroalgae is currently used as functional food ingredients, natural nutraceuticals, biomedical materials, cosmetic formulations, as well as in other products that promote human health. One of the major limitations in the search for new extracts or natural products with biological action is the lack of available biomass for studies and even for their bioprospection. In this context, the availability of beach-cast marine algae is a sustainable and highly productive alternative. The main objective of this study was to evaluate the chemical and bioactive potential of extracts from 15 materials of beach-cast marine algae collected from the Brazilian coast to provide subsidies that allow identifying the potentialities and its uses as functional product. The findings showed that the highest antioxidant activities were found in extracts from brown beach-cast algae followed by the extracts of red beach-cast algae, and the lowest activities were detected in the green beach-cast species. The most efficient extracts of beach-cast species with antioxidant properties were from Dictyopteris jolyana, Zonaria tournefortii, and Osmundaria obtusiloba. Regarding antiviral activity, the aqueous extract of Codium isthmocladum and methanolic extracts from D. jolyana, Z. tournefortii Alsidium seaforthii, Spiridia clavata and O. obtusiloba were highly promising, reaching inhibition percentage above 90%. The extracts of Z. tournefortii, A, seaforthii and C. isthmocladum showed high cytotoxicity activity against the tumoral cells strains HL60 (leukemia) and HTC116 (colon) and did not show any cytotoxicity activity against non-tumoral human cells (HGF1). Currently, the large amount of beach-cast seaweeds deposited on the beaches of Brazil is collected and treated as trash, being incinerated or disposed in landfills by the government. Instead of using public resources and making efforts for the removal of this biomass, it is possible to propose different uses for the Brazilian beach-cast seaweeds and transform it into applications for several sectors. Due to the antioxidant, antiviral, nutritional, photoprotective and cytotoxic properties reported for macroalgae, such applied features bring environmental benefits by mitigating coastal pollution generating a usable resource, in addition to ensuring sustainable social and economic development. The review data shown in the literature of Brazilian beach-cast algae shows the relevance and innovation of this study. This is the first report evaluating chemical composition, antioxidant potential, antiviral activity, cytotoxicity potential and photoprotection of extracts from beach-cast algae from the Brazilian coast. The potential of beach-cast seaweeds provides raw-material for several applications, combined with the large amount available on the beaches of certain regions at the Brazilian coast can be better exploited. The present study significantly contributes to increasing knowledge of Brazilian beach-cast algae and their potential uses as well as t...

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Antimicrobial (including antimollicutes), antioxidant and anticholinesterase activities of Brazilian and Spanish marine organisms – evaluation of extracts and pure compounds

Cited by 19 publications

References 42 publications

Screening of the antimicrobial activity of marine sponge extracts from Martinique

Screening of the antimicrobial activity of marine sponge extracts from Martinique

Antibacterial activity of methanol extracts of the leaves of three medicinal plants against selected bacteria isolated from wounds of lymphoedema patients

Caracterização química, potencial antioxidante e atividade biológica de macroalgas arribadas do litoral brasileiro

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