Anti-psoriatic activity of flavonoids from Cassia tora leaves using the rat ultraviolet B ray photodermatitis model

Vijayalakshmi, A.; Geetha, Madhira

doi:10.1016/j.bjp.2014.07.010

Cited by 36 publications

(17 citation statements)

References 15 publications

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“…Amongst all, silver nanoparticles (AgNPs) have 15 attained promising applications in nanotechnology because of 16 their good electrical conductivity, chemical stability, catalytic 17 and antibacterial properties [2]. Physical and chemical methods 18 also employed for synthesis of AgNPs, but due to their toxicity of 19 chemicals used as reducing agent, the bio-synthetic route was 20 reported as clean, non toxic and environmentally acceptable 21 [3][4][5][6][7][8]. The use of plants and its extracts as reducing agents for the 22 synthesis of nanoparticles is more advantage prospectively over 23 microorganisms due to ease scale up and less bio hazard [ [19], antimutagenicity [20], anticancer [21], antihyperlipidemic 36 [22], anthelmintic [23], antinociceptive [24], antifeedant and 37 larvicidal activities [25].…”

mentioning

confidence: 99%

Biosynthesis of silver nanoparticles using Cassia tora leaf extract and its antioxidant and antibacterial activities

Saravanakumar

Ganesh

Jayaprakash³

et al. 2015

Journal of Industrial and Engineering Chemistry

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mentioning

confidence: 99%

Biosynthesis of silver nanoparticles using Cassia tora leaf extract and its antioxidant and antibacterial activities

Saravanakumar

Ganesh

Jayaprakash³

et al. 2015

Journal of Industrial and Engineering Chemistry

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“…Among flavones, cynaroside (luteolin-7-O-β-D-glucopyranoside) prevents H 2 O 2 -induced apoptosis in H9c2 [23] and SH-SY5Y [24] cell lines by reducing the endogenous production of ROS. Furtheremore, cynaroside is very effective against Gram-negative bacteria [25] and showed significant antipsoriatic activity using photodermatitis model [26] .…”

Section: Resultsmentioning

confidence: 99%

Polar Bioactive Constituents From Aerial Parts Of thymus Longicaulis c. Presl

D’Abrosca¹

2016

LHBS

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Thymus longicaulis C. Presl., belonging to the Lamiaceae family, is a small aromatic perennial herb typical of the Mediterranean vegetation. This species, known in traditional phytoteraphy of Italy, has been extensively investigated in terms of chemical analysis and biological activity of its essential oils. Nevertheless, few data are available in the literature, regarding the chemical characterization of polar components of T. longicaulis. In this study, the phytochemical investigation of methanol extract of T. longicaulis through different chromatographic techniques, led to the isolation of thirteen compounds. The structures of rosmarinic acid and two derivatives, as well as that of flavones, triterpenes and a lignan have been elucidated on the basis of extensive NMR spectroscopic analyses. The evaluation of DPPH radical scavenging activity of pure compounds has been performed.

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“…The histological studies reveal that the skin section treated/induced with Imiquimod showed a degenerative changes in skin tissue shows thickened epidermis, increased keratinization decrease in percentage of orthokeratotic regions, elongation of rette ridges, capillary loop dilation with minimal grade lesion of Munro ҆ s microabcess, vacuolization which indicates the severe damage of skin tissue. Animals treated with Retino-A and BOAE, MSEE shows normal cytoarchitecture of skin tissue indicates regenerative changes [34].…”

Section: Discussionmentioning

confidence: 99%

“…The histopathology slides helped in evaluating different parameters like inflammatory cells, neutrophils, etc,. [ Fig.8] [34].…”

Section: Histological Slidesmentioning

confidence: 99%

Evaluation of Antipsoriatic Activity of Aqueous Extract of Brassica Oleracea Var. Capitata and Ethanolic Extract of Mentha Spicata Leaves on Imiquimod-Induced Psoriasis-Like Dermatitis

Reddy

2019

Asian J Pharm Clin Res

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Objective: The objective of this study is to evaluate the antipsoriatic activity of aqueous extract of Brassica oleracea var. capitata leaves (BOAE) and ethanolic extract of Mentha spicata leaves (MSEE) on Imiquimod-induced Psoriasis-like dermatitis. Methods: Imiquimod induction method for psoriasis-like dermatitis was used for the evaluation of antipsoriatic activity. Extracts were tested at a dose of 100 mg/kg body weight (b.wt.) and 400 mg/kg b.wt. in Swiss albino mice. These test doses were compared with the Retino-A (0.025%) treated group which serves as a standard group. Parameters studied in the test include changes in body weight, spleen weight and spleen index, neutrophils, lymphocytes, eosinophils, monocytes, hemoglobin, red blood cells, platelets, packed cell volume, mean corpuscular volume, mean corpuscular hemoglobin (MCH), MCH concentration, epidermal thickness, erythema, desquamation, skin thickness, superoxide dismutase, catalase, lipid peroxidation of skin and percentage orthokeratotic values, drug activity, and relative epidermal thickness. Results: MSEE at dose of 400 mg/kg b.wt has shown more effect when compared with MSEE at low dose, BOAE topical and oral. Conclusion: From the study, it was concluded that the above extracts have promising anti-psoriatic activity.

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Anti-psoriatic activity of flavonoids from Cassia tora leaves using the rat ultraviolet B ray photodermatitis model

Cited by 36 publications

References 15 publications

Biosynthesis of silver nanoparticles using Cassia tora leaf extract and its antioxidant and antibacterial activities

Biosynthesis of silver nanoparticles using Cassia tora leaf extract and its antioxidant and antibacterial activities

Polar Bioactive Constituents From Aerial Parts Of thymus Longicaulis c. Presl

Evaluation of Antipsoriatic Activity of Aqueous Extract of Brassica Oleracea Var. Capitata and Ethanolic Extract of Mentha Spicata Leaves on Imiquimod-Induced Psoriasis-Like Dermatitis

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