A very rare mass mimicking paraganglioma in the parapharyngeal area: extraskeletal osteosarcoma

Aslan, Mehmet; Şamdancı, Emine

doi:10.1016/j.bjorl.2020.11.012

Cited by 4 publications

(4 citation statements)

References 8 publications

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“…As it is a rare condition and with numerous sequelae involved, the recognition of the presence of concomitant paralyzes is an important step in the diagnosis and treatmen t5, 6,20,21 Tumors of the parapharyngeal space are rare, with the four major primary tumors being: deep parotid lobe masses, minor salivary gland lesions, neuromas and glottic tumors. 23,24 The vagus (Xth) and hypoglossal (XIIth) nerves are of great relevance for fundamental processes in human life, such as communication and feeding, since they are responsible, respectively, for the innervation of most of the laryngeal muscles, pharyngeal constrictor muscles, airway smooth muscle, intestine [25][26][27] and tongue mobility (28)(29)(30)(31). Corroborating the findings in the literature 21,32 the isolated lesion of the hypoglossal nerve is usually unilateral and considered a rare postoperative complication with multifactorial causes.…”

Section: Discussionmentioning

confidence: 99%

Speech therapy rehabilitation in Tapia´s syndrome: case report

Spacassassi¹,

Pereira²

2023

IPMRJ

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Tapia’s syndrome is charaterized by damage to the recurrent laryngeal nerve (branch of the Xth) and the hypoglossal nerve (XIIth), and in some cases, the accessory nerve (XIth) may also be affected. The cause is usually trauma to the point where the hypoglossal and vagus intersect. This results in lingual hemiparesis, vocal fold paralysis and dysphagia. Objective: to present the results of speech therapy in a case that evolved with Tapia´s Syndrome after the excision of a tumour in the parapharyngeal space. Case report: male patient, 71 years old, submitted to excision of a Schwannoma in the vagus nerve, with parotid invasion. Evolved with: dysarthria; severe dysphagia; lack of flow control; dysphonia; facial paralysis and dyspnoea. Six months after surgery, thyroplasty and botulinum toxin injections were performed in the cricopharyngeal muscle and salivary glands, which ensured a temporary improvement in voice and control of salivary flow. Results: The rehabilitation process consisted of stimulating the mobility of the muscles responsible for facial mimicry, reintegration of stomatognathic functions, swallowing and voice. After two years of speech therapy, the patient showed improvement in the mobility of the facial mimic muscles, a slight improvement in the vocal pattern, in addition to an improvement in the breathing pattern. Conclusion: despite the limitations and functional complexities encountered in the postoperative period, there was evidence of improvement in the patient’s quality of life after performing clinical procedures combined with the therapeutic process.

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Section: Discussionmentioning

confidence: 99%

Speech therapy rehabilitation in Tapia´s syndrome: case report

Spacassassi¹,

Pereira²

2023

IPMRJ

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“…reported a 69-year-old man with ESOS in the parapharyngeal region who presented with pain in the left parapharyngeal region as well as dysphagia, hoarseness, and speech disturbances with internal calcification, which was initially thought to be from the left carotid bifurcation. Therefore, it was considered a paraganglioma mass containing punctate calcified foci ( 1 ). Shankar et al.…”

Section: Discussionmentioning

confidence: 99%

“…Extraskeletal osteosarcoma (ESOS) is a rare malignant soft tissue sarcoma, which is considered a subtype of osteosarcoma ( 1 ). ESOS has histologic similarities to primary bone osteosarcoma except for the attachment to the bone or the periosteum.…”

Section: Introductionmentioning

confidence: 99%

“…ESOS is a type of osteosarcoma that occurs in extraskeletal organs and soft tissues ( 2 ), accounting for 1% of all soft tissue sarcomas and 4% of osteogenic osteosarcomas ( 3 ). It has been reported that ESOS mostly occurs in the lower extremity, shoulder girdle, upper extremity, retroperitoneum, thigh, and hip, as well as the head and neck, gallbladder, heart, liver, kidney, bladder, breast, esophagus, prostate, spermatic cord, penis, larynx, tongue, mediastinum, lung, brain, rectum, and omentum; however, the most common location is the soft tissue of the thigh ( 1 , 2 , 4 – 6 ). ESOS is divided into primary and secondary types, and given its rarity, it is difficult to diagnose.…”

Section: Introductionmentioning

confidence: 99%

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A Primary Extraskeletal Osteosarcoma of the Spleen: Rare Case Report

Pan

Wang

Lin³

et al. 2022

Front. Oncol.

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Extraskeletal osteosarcoma is a rare malignant soft-tissue sarcoma that is difficult to diagnose. Surgery is a common treatment, although chemotherapy and radiotherapy are also used. Patients at risk of bleeding can undergo embolization combined with resection. The occurrence of primary splenic extraskeletal osteosarcoma in humans does not seem to have been reported in the literature. A 50-year-old woman who complained of pain in the left upper abdomen for 1 day was initially diagnosed with “splenic hemangioma with a high possibility of rupture and bleeding” and urgently underwent digital subtraction angiography, combined with splenic arteriography and embolization. Abdominal pain worsened 2 days postoperatively, with a hemoglobin level of 106.0 g/L. Consequently, emergency laparotomy combined with splenectomy was performed. The clinical and imaging features, pathological diagnosis, and embolization treatment of this case were analyzed retrospectively. CT of the upper abdomen revealed splenomegaly, an irregular low-density shadow in the spleen, and a flake-like calcification in the lateral margin of the left kidney. Nuclear MRI of the upper abdomen showed splenomegaly and a mass (approximately 8.4 cm × 5.7 cm × 6.3 cm) below the spleen with clear boundaries—this exhibited an uneven signal, which was slightly low in T1-weighted imaging (T1WI) and slightly high in T2-weighted imaging (T2WI). Several small cystic lesions or cystic cavities were observed in the mass, which exhibited a longer T2 signal. During the enhanced scan, the signal of the lesion showed progressive enhancement, and the enhancement range increased in the delayed phase scan, as well as a hematoma below the spleen capsule and calcification below the lesion (nodular T1WI/T2WI hypointense, approximately 3.3 cm × 3.6 cm). Postoperative biopsy pathology showed splenic soft tissue tumor: at low magnification, the multinucleated giant cells were scattered; at medium magnification, osteoclast-like multinucleated giant cells were observed; and at high magnification, lace- or grid-like tumor osteogenesis was detected. Immunohistochemistry showed that the expression of CD31, CD34, F8, s-100, desmin, SMA, and CD99 was negative, whereas the expression of β-catenin, BCL-2, SATB-2, and P16 was positive. CD68 and MDM-2 showed low expression, while 50% of the cells were positive for Ki-67 expression. No abnormal concentration of radioactivity was found on the bone scan with 99mTc-MDP after the operation, further ruling out the occurrence of other bone tumors. The patient was diagnosed with primary extraskeletal osteosarcoma. It is necessary for multidisciplinary teams to diagnose malignant extraskeletal osteosarcomas.

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