Effect of topical corticosteroids on nasal patency after acute positive airway pressure exposure

Balsalobre, Leonardo; Figueiredo, Aline Bruno; Pezato, Rogério; Fujita, Reginaldo Raimundo

doi:10.1016/j.bjorl.2019.09.011

Cited by 2 publications

(3 citation statements)

References 17 publications

(22 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Hence, treatment for allergic rhinitis is important in the continuation of CPAP treatment. The use of intranasal corticosteroids for rhinitis symptoms has been reported to improve CPAP adherence [16,28]. We also previously reported that nasal surgery for nasal obstruction improves not only nasal resistance but also CPAP adherence as well as daytime sleepiness, as evaluated by ESS [14].…”

Section: Discussionmentioning

confidence: 99%

“…Therefore, the use of CPAP therapy may be affected by symptoms of AR, especially in the spring season in Japan due to JCP. There are few reports concerning the effect of AR with nasal congestion and obstruction on OSA [15,16]. Nakayama et al reported that seasonal changes are present in Japanese children with clinically symptomatic OSA and differ among younger (< 6 years of age) and older (6 ≥ years) children, with global trends toward improved apnea hypopnea index (AHI) during summer in younger children [15].…”

Section: Introductionmentioning

confidence: 99%

“…They suggested that nasal obstruction may have an important role in severity of pediatric OSA. Regarding adult patients with OSA who are treated with CPAP therapy, intranasal corticosteroid therapy for AR improved objective and subjective parameters of nasal patency after acute exposure of the nasal cavity to positive pressure [16]. Therapy for JCP is commonly chosen based on the severity and symptoms at peak pollen dispersal and amounts of pollen dispersal.…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Impact of antiallergy agents on CPAP therapy and sleep quality with spring pollinosis in Japanese

et al. 2023

View full text Add to dashboard Cite

Purpose Allergic rhinitis (AR) is associated with obstructive sleep apnea (OSA) and nasal obstruction causes decreased adherence to continuous positive airway pressure (CPAP). The purpose is to evaluate the effects of antiallergic agents on CPAP adherence and sleep quality. Methods A longitudinal study was made of patients who use CPAP for OSA and treated with antiallergy agents for spring pollinosis. We compared the Pittsburgh Sleep Quality Index (PSQI), Epworth Sleepiness Scale (ESS), nasal symptoms scores (NSS), and data from CPAP before and after treatment. Then, we classified the subjects into two groups based on the baseline PSQI score: one group without a decreased sleep quality (PSQI < 6) and the other group with decreased sleep quality (PSQI ≥ 6). Results Of 28 subjects enrolled, 13 had good sleep quality and 15 had poor sleep quality. PSQI showed significant improvements after medication (p = 0.046). ESS showed no significant differences after AR medication (p = 0.565). Significant improvement was observed after the prescription of antiallergy agents in all items of NSS (sneezing, p < 0.05; rhinorrhea, p < 0.01; nasal obstruction, p < 0.01; QOL, p < 0.01). The percentage of days with CPAP use more than 4 h increased significantly after the administration of rhinitis medication (p = 0.022). In the intragroup comparisons of PSQI ≥ 6 group, PSQI decreased significantly (p < 0.05). For the NSS in intragroup comparisons of PSQI ≥ 6 group, all parameters showed significant improvement (sneezing, p = 0.016; rhinorrhea, p = 0.005; nasal obstruction, p < 0.005; QOL, p < 0.005). ConclusionThe use of antiallergy agents can improve CPAP adherence and sleep quality in patients with OSA on CPAP.

show abstract

Section: Discussionmentioning

confidence: 99%