First molecular typing of Mycobacterium avium subspecies paratuberculosis identified in animal and human drinking water from dairy goat farms in Brazil

Espeschit, Isis Freitas; Souza, M. C. C.; Lima, Magna Coroa; Moreira, Maria Aparecida Scatamburlo

doi:10.1016/j.bjm.2017.06.005

Cited by 5 publications

(3 citation statements)

References 30 publications

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“…It indicates that type C is the predominant type in cattle in Shandong Province, China. It was consistent with most other previous studies, and type C is the predominant type in the world [24,25,[32][33][34][35][36][37][38][39][40].…”

Section: Discussionsupporting

confidence: 93%

Characteristics and Epidemiological Investigation of Paratuberculosis in Dairy Cattle in Tai’an, China

Cheng

Liu

Wang

et al. 2020

BioMed Research International

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Paratuberculosis, a chronic and sometimes fatal disease of ruminants, is caused by Mycobacterium avium subsp. paratuberculosis (MAP). In this study, we examined paratuberculosis cases among 2–4-year-old dairy cows at farms in Shandong Province, China. Paratuberculosis cases were diagnosed based on clinical symptoms, pathological autopsy, and histopathological inspection. Characteristics of paratuberculosis in the affected dairy cattle included poor body condition, persistent diarrhea, subcutaneous edema, granulomatous ileitis (multibacillary), mesenteric lymphadenitis, and hepatitis. Acid-fast bacilli from fecal specimens and lymphocytes were putatively identified as MAP based on Ziehl-Neelsen staining, then confirmed using polymerase chain reaction-based testing and matrix-assisted laser desorption/ionization time-of-flight mass spectrometry analyses. Overall, only one MAP strain was isolated from a herd with symptomatic diarrhea. However, analysis of 586 serum samples from nine herds in Tai’an City revealed that 66.7% of herds and 14.2% of animals were seropositive for MAP. Our findings suggest that paratuberculosis is widely prevalent and therefore a significant threat to the dairy industry in Tai’an City, Shandong Province, China.

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Section: Discussionsupporting

confidence: 93%

Characteristics and Epidemiological Investigation of Paratuberculosis in Dairy Cattle in Tai’an, China

Cheng

Liu

Wang

et al. 2020

BioMed Research International

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“…The results of a blind study from three independent laboratories, which confirms a higher prevalence of viable MAP in CD patients than in controls [ 79 ], the concurrent increase in the herd prevalence of JD and CD over the same period in the USA [ 8 , 80 ] and the reported remission and cure of CD patients treated with antibiotics against MAP [ 81 , 82 ] lend more credence to the theory that MAP could be a cause of CD. In one study [ 83 ], an association between the presence of MAP DNA in the intestinal biopsy tissues of CD patients and the consumption of unpasteurized dairy products in Brazil was found. In view of this possible connection, the finding of MAP in pasteurized dairy products is believed to raise a serious public health concern [ 68 ].…”

Section: The Role Of Map In Idiopathic Inflammatory Bowel Disease mentioning

confidence: 99%

Paratuberculosis: A Potential Zoonosis and a Neglected Disease in Africa

et al. 2020

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The Mycobacterium avium subspecies paratuberculosis (MAP) is the causative agent of paratuberculosis, which is an economically important disease of ruminants. The zoonotic role of MAP in Crohn’s disease and, to a lesser extent, in ulcerative colitis, the two major forms of idiopathic inflammatory bowel disease (IIBD), has been debated for decades and evidence continues to mount in support of that hypothesis. The aim of this paper is to present a review of the current information on paratuberculosis in animals and the two major forms of IIBD in Africa. The occurrence, epidemiology, economic significance and “control of MAP and its involvement IIBD in Africa” are discussed. Although the occurrence of MAP is worldwide and has been documented in several African countries, the epidemiology and socioeconomic impacts remain undetermined and limited research information is available from the continent. At present, there are still significant knowledge gaps in all these areas as far as Africa is concerned. Due to the limited research on paratuberculosis in Africa, in spite of growing global concerns, it may rightfully be considered a neglected tropical disease with a potentially zoonotic role.

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“…Tiene una estructura de pared celular compleja que contiene ácidos ARTÍCULOS ORIGINALES micólicos y varios lípidos similares a los de otros miembros de este género, pero esta en particular tiene un crecimiento más lento (Rathnaiah et al, 2017). La variabilidad genética de la MAP tiene importantes implicaciones para el diagnóstico y control de la PTB, debido a diferencias en la tasa de crecimiento, virulencia y características epidemiológicas (Espeschit et al, 2018).…”

Section: Agente Etiológicounclassified

Paratuberculosis bovina, revisión de literatura

et al. 2021

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La paratuberculosis bovina (PTB) es una enfermedad crónica causada por el bacilo Mycobacterium avium subespecie paratuberculosis (MAP). Tiene distribución a nivel mundial y genera pérdidas económicas para los productores por el bajo rendimiento productivo de los animales y el amplio periodo de incubación, en el cual es excretada a través de la materia fecal sin signos clínicos. Así mismo, se reporta que los animales más susceptibles de contraer la enfermedad son los terneros. Entre los métodos de diagnóstico utilizados para la MAP, están PCR, ELISA, cultivo bacteriano de materia fecal, el examen para detección de MAP en muestras de tejido y la prueba de hipersensibilidad cutánea retardada Johnina intradérmica. La MAP es una bacteria con posible potencial zoonótico por su relación con la enfermedad de Crohn. Debido a que no hay tratamiento para la PTB, se deben intensificar los mecanismos de control en las producciones.

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First molecular typing of Mycobacterium avium subspecies paratuberculosis identified in animal and human drinking water from dairy goat farms in Brazil

Cited by 5 publications

References 30 publications

Characteristics and Epidemiological Investigation of Paratuberculosis in Dairy Cattle in Tai’an, China

Characteristics and Epidemiological Investigation of Paratuberculosis in Dairy Cattle in Tai’an, China

Paratuberculosis: A Potential Zoonosis and a Neglected Disease in Africa

Paratuberculosis bovina, revisión de literatura

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