Recent HCV genotype changing pattern in the Khyber Pakhtunkhwa province of Pakistan; is it pointing out a forthcoming problem?

HCV Treatment with Sofosbuvir in Pakistan; Current Scenario and Future Perspective

“…There are several studies investigating the prevalence of HCV genotypes from different areas of Pakistan. Recently, we have reviewed the available data from Pakistan regarding the prevalence of HCV genotypes and the data showed that 3a genotype is the most prevalent (63%) followed by genotypes 1 (09%) and 2 (08%) along with an alarming number of diagnostically untypable viral genotypes (14%) in the local community [8][9] .…”

Does HCV Prevalence in Blood Donors Reflects the Incidence in General Population? A Study for Global Impact

“…The management of chronic HCV infection is very difficult and can have a substantial effect on the economic status of the individuals, society and ultimately the country. The current standard of care antiviral therapies includes interferon based and interferon free direct acting antivirals (DAAs) [6]. Interferon based regimes have side effects where as DAAs are very costly to manage for treatment of all infected individuals [7,8].…”

Sexual Dimorphism of Hepatocellular Carcinoma in Pakistan

“…Several studies are being conducted in Pakistan showing high viral infectious burden ultimately or not leading to HCC [1]. In Pakistan, prevalence of HCV is 4.5-8.0% ranking Pakistan second highest with HCV burden [13][14][15][16][17].…”