Chikungunya: bending over the Americas and the rest of the world

Madariaga, Miguel G.; Ticona, Eduardo; Resurrecion, Cristhian

doi:10.1016/j.bjid.2015.10.004

Cited by 56 publications

(43 citation statements)

References 60 publications

(63 reference statements)

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“…Ae. albopictus is more common in Asia, and has become worthy of mentioning in the Southeast of the United States and the Caribbean region 6 . CHIKV currently circulating in America seems to no longer be related to the African lineage, but to strains documented in Asia and the Phillipines 2, 4 .…”

Section: Introductionmentioning

confidence: 99%

“…The transmission cycle, although originally merely sylvatic between primates and forest mosquitoes, has developed an alternate urban cycle involving humans 1, 6 . Aedes as vectors are capable of spreading the virus after biting a viremic human, after which CHIKV replicates in salivary glands of the female mosquito and then a new bite of a healthy host takes place 6, 7 .…”

Section: Introductionmentioning

confidence: 99%

“…Aedes as vectors are capable of spreading the virus after biting a viremic human, after which CHIKV replicates in salivary glands of the female mosquito and then a new bite of a healthy host takes place 6, 7 . After the infectious bite, the incubation period of CHIKV ranges from 1–12 days before clinical onset of symptoms 1, 6 . The appearance of clinical manifestations of the febrile syndrome coincides with viremia settling in during a period of 5–7 days, when viral load can be as high as 10 9 viral genome copies per milliliter 3 .…”

Section: Introductionmentioning

confidence: 99%

“…The appearance of clinical manifestations of the febrile syndrome coincides with viremia settling in during a period of 5–7 days, when viral load can be as high as 10 9 viral genome copies per milliliter 3 . Most recently, cases of vertical transmission have been reported, but it is indeed rare, and transmission through nursing has not been proven 1, 6, 8 .…”

Section: Introductionmentioning

confidence: 99%

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Cardiovascular involvement and manifestations of systemic Chikungunya virus infection: A systematic review

et al. 2017

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Background: In the last three years, chikungunya virus disease has been spreading, affecting particularly the Americas, producing more than two million cases. In this setting, not only new disease-related epidemiological patterns have been found, but also new clinical findings have been reported by different research groups. These include findings on the cardiovascular system, including clinical, electrocardiographic and echocardiographic alterations. Methods: We performed a systematic review looking for reports about cardiovascular compromise during chikungunya disease. Cardiac compromise is not so common in isolated episodes; but countries where chikungunya virus is an epidemic should be well informed about this condition. We used 6 bibliographical databases as resources: Medline/Pubmed, Embase, ScienceDirect, ClinicalKey, Ovid and SciELO. Dengue reports on cardiovascular affectation were included as well, to compare both arbovirus’ organic affectations. Articles that delved mainly into the rheumatic articular and cutaneous complications were not considered, as they were not in line with the purpose of this study. The type of articles included were reviews, meta-analyses, case-controls, cohort studies, case reports and case series. Results: Originally based on 737 articles, our reviewed selected 40 articles with 54.2% at least mentioning CHIKV cardiovascular compromise within the systemic affectation. Cardiovascular manifestations can be considered common and have been reported in France, India, Sri Lanka, Malaysia, Colombia, Venezuela and USA, including mainly, but no limited to: hypotension, shock and circulatory collapse, Raynaud phenomenon, arrhythmias, murmurs, myocarditis, dilated cardiomyopathy, congestive insufficiency, heart failure and altered function profile (Troponins, CPK). Conclusions: Physicians should be encouraged to keep divulgating reports on the cardiovascular involvement of chikungunya virus disease, to raise awareness and ultimately encourage suitable diagnosis and intervention worldwide.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Cardiovascular involvement and manifestations of systemic Chikungunya virus infection: A systematic review

et al. 2017

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“…In terms of morbidity and mortality, dengue is nowadays considered the most important viral disease transmitted by mosquitoes, constituting a serious public health problem of urban centers from South & Central America, Southeast Asia and West Pacific tropical areas [5] . Chikungunya disease, which shown symptoms similar to dengue's is caused by Chikungunya virus (CHIKV), a RNA virus member of the Alphavirus genus in the family Togaviridae, first described in Africa, but which migrated later to Asia and Europe, after small mutations [6][7][8] . These disease symptoms, which may persist for months or even years, are debilitating, causing fever, arthralgia or severe arthritis and itchy skin [9] .…”

Section: Introductionmentioning

confidence: 99%

Chemical Characterization and Larvicidal Activity of Essential Oil from Aniba duckei Kostermans against Aedes aegypti

Teles¹,

Filho²,

Souza³

2017

IJLSSR

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ABSTRACT-Aedes aegypti mosquito is the major vector of zika, chikungunya, and dengue fever. These diseases incidence has been growing rapidly in many points of the globe in the past few years. And because there's no vaccine for them yet, the best way to fight those diseases is to attack their vector, specially by eliminating potential sites for its oviposition and larvae growth. Nowadays, organophosphorus insecticides are used in increasing doses, which targets Aedes aegypti resistant populations. Aniba duckei Kostermans, which is known as rosewood and belongs to the Lauraceae family, is a species with trees up to 30 meters tall and 1 meter in trunk diameter. It's essential oil is used in perfumery due to its high content of linalool. This research identified the components of essential oil from Aniba duckei Kostermans thin branches and leaves and then applied it as larvicide against Aedes aegypti, and its effects were measured by calculation of concentration at which half larvae die (LC 50 ). Average yield found for oil by plant was 1.93% by mass. The major component in rosewood essential oil is linalool, whose concentration was found 89.34% by mass. LC 50 for the essential oil was 250.61 (±2.20) µg mL -1 , for l-linalool, 279.89 (±2.12) µg mL -1 , and for dl-linalool was 346.73 (±2.14) µg mL -1 .

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