Rothia aeria endocarditis in a patient with a bicuspid aortic valve: case report

Abstract

Rothia aeria is an uncommon pathogen mainly associated with endocarditis in case reports. In previous reports, endocarditis by R. aeria was complicated by central nervous system embolization. In the case we report herein, endocarditis by R. aeria was diagnosed after acute self-limited diarrhea. In addition to the common translocation of R. aeria from the oral cavity, we hypothesize the possibility of intestinal translocation. Matrix-assisted laser desorption ionization-time of flight mass spectrometry and genetic sequencing are important tools that can contribute to early and more accurate etiologic diagnosis of severe infections caused by Gram-positive rods.

Rothia aeria vertebral discitis/osteomyelitis in an immunocompetent adult: Case report and literature review

“…Our review of the literature revealed seventeen case reports of non-dental infection caused by R. aeria ( Table 1 ). The most common manifestations of R. aeria infection were endocarditis noted in eight cases [4] , [5] , [6] , [7] , [8] , [9] , [10] , [11] and respiratory tract infection noted in four cases [12] , [13] , [14] , [15] . Joint infection [16] , [17] , skin abscess [18] and tubal-ovarian abscess [19] caused by R. aeria were less commonly described.…”

“…Joint infection [16] , [17] , skin abscess [18] and tubal-ovarian abscess [19] caused by R. aeria were less commonly described. Only six reported cases were in immunocompetent patients [4] , [5] , [7] , [9] , [10] , [11] , all of which manifested as endocarditis.…”

Analysis of culturable microbiota present in the stomach of children with gastric symptoms

“…This bacterium is a newly discovered opportunistic pathogen known to colonize the human oral cavity [49] and the upper gastrointestinal tract [50]. It has also been isolated from patients with acute diarrhea and recurrent fever from blood samples [51]. When the gastric mucosa is destroyed by infection with H. pylori, Rothia aeria might enter the blood and induce bacteremia.…”

Endocarditis por Rothia aeria

“…El género Rothia comprende actualmente 6 especies nombradas, 2 de las cuales se consideran clínicamente relevantes: Rothia dentocariosa 1, 2 y Rothia mucilaginosa 3 . Otro miembro del género, Rothia aeria, un grupo de taxón llamado provisionalmente Rothia dentocariosa genomovar II 2 , es una causa rara de infecciones humanas 4,5 . Rothia spp., se asocian comúnmente con caries dental y enfermedad periodontal 6,7 .…”