Erythrovirus B19 induced persistent bicytopenia in a healthy child

Jain, Mili; Oberoi, Gurleen; Kumar, Rashmi; Kumar, Ashutosh

doi:10.1016/j.bjhh.2017.04.002

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2019

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“…In addition, the megakaryocytes were increased, in clusters, with predominance of early forms [compensatory response to thrombocytopenia, Figure 2]. [3] A final diagnosis of HL mixed cellularity stage III B bulky disease with ITP was made.…”

Section: Case Reportmentioning

confidence: 99%

Hodgkin Lymphoma Presenting as Immune Thrombocytopenia

Jain

Pandey

Verma

et al. 2019

Indian Journal of Medical and Paediatric Oncology

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Immune thrombocytopenia (ITP) in lymphoid malignancies has been observed primarily in relation to chronic lymphoproliferative disorders. ITP in Hodgkin lymphoma (HL) is a rare presentation, most often reported at follow-up. We report a case of a 12-year-old female presenting with symptomatic thrombocytopenia at the time of diagnosis of HL. The patient had stage III B bulky disease with HL mixed cellularity subtype on histology. The patient was treated with adriamycin, bleomycin, vinblastine, and dacarbazine regime along with local radiation therapy and is in complete remission at 18 months of follow-up. The treatment of underlying lymphoma in such cases resolves thrombocytopenia.

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Section: Case Reportmentioning

confidence: 99%