Anesthesia for bariatric surgery in patient with mitochondrial myopathy – case report

Melonio, Carlos Eduardo Coimbra; Vieira, Ciro Bezerra; Leal, Plínio da Cunha; Oliveira, Clair Motos de; Servin, Elizabeth Teixeira Noguera; Gomes, Lyvia Maria Rodrigues de Sousa; Moura, Ed Carlos Rey

doi:10.1016/j.bjane.2020.09.009

Cited by 3 publications

(2 citation statements)

References 5 publications

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“…Interventions include gastrostomy, cataract surgery, thyroid lobectomy, lipoma excision, cochlear implantation, amongst others. 16 , 17 , 18 , 19 , 20 , 21 Complications after anaesthesia have been reported, but the rarity of the disease, genetic and clinical heterogeneity of patients, ad hoc nature of disease management, and comorbid neurologic and metabolic sequelae greatly limit efforts to define VA-induced toxicities in the clinic. Accordingly, animal studies are of great utility for probing disease mechanisms and testing the effects of anaesthetics.…”

mentioning

confidence: 99%

Volatile anaesthetic toxicity in the genetic mitochondrial disease Leigh syndrome

Spencer,

Mulholland,

Snell

et al. 2023

British Journal of Anaesthesia

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mentioning

confidence: 99%

Volatile anaesthetic toxicity in the genetic mitochondrial disease Leigh syndrome

Spencer,

Mulholland,

Snell

et al. 2023

British Journal of Anaesthesia

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“…To avoid uncontrolled catabolism, intravenous fluids and nutrition are maintained until the patient is discharged. 53 Organ transplantation: In certain situations, patients with electron transport chain deficit may benefit from a liver transplant. It was recorded that, there are favourable benefits with heart transplantation's in cardiomyopathy caused by mitochondrial dysfunction.…”

Section: Anesthesiamentioning

confidence: 99%

Mitochondrial diseases: past, present, and future

AkL,

Afsah,

A Saad

2022

UNOAJ

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Mitochondria are membrane-bound organelles found in almost all eukaryotic cells. Mitochondria are in charge of mastering and organizing cellular energy production in order to sustain life. Two genomic systems are responsible for mitochondrial biogenesis: nucli-genomes and another set of mitochondrial genes (mtDNA). MtDNA encodes 13 proteins that are required for respiratory chain function. Mitochondria play a role in a variety of cellular processes, including calcium signaling, cell cycle, differentiation, and cell death. Mitochondrial shape indicates good health, and their location in the cell is essential for their function. Mitochondrial dysfunction has been linked to Alzheimer's disease, metabolic disorders, ischemic brain, heart, and neurodegenerative diseases. In this section, we exemplify the clinical implications of mitochondrial diseases in terms of acquired defects

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Propofol

2022

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Anesthesia for bariatric surgery in patient with mitochondrial myopathy – case report

Cited by 3 publications

References 5 publications

Volatile anaesthetic toxicity in the genetic mitochondrial disease Leigh syndrome

Volatile anaesthetic toxicity in the genetic mitochondrial disease Leigh syndrome

Mitochondrial diseases: past, present, and future

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