Ketamine–propofol sedation in circumcision

Güleç, Handan; Şahin, Şaziye; Ozayar, Esra; Degerli, Semih; Bercin, Fatma; Özdemir, Osman

doi:10.1016/j.bjane.2014.03.002

Cited by 2 publications

(1 citation statement)

References 23 publications

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“…Meanwhile, Sung et al administered propofol as a bolus after 3 minutes of continuous syringe pump remifentanyl and 5 minutes after the bolus of fentanyl intravenously (Sung et al, 2020). Gulec (2015) conducted a study comparing remifentanil-propofol with fentanylpropofol in pediatric circumcision surgery. They found that the recovery time in patients receiving remifentanil-propofol was 4.2 (Mean= 4.2; SD= 2.8) minutes and fentanyl-propofol was 4.2 (Mean= 4.2; SD= 2.8) minutes and fentanyl-propofol was 9.4 (Mean= 9.4; SD= 3.2) minutes with a significant difference (P<0.05).…”

Section: Discussionmentioning

confidence: 99%

Comparison of The Effectiveness of Remifentanyl versus Fentanyl in Pediatric Undergoing Methotrexate Therapy

Purwoko¹,

Putro²,

Pamungkas³

et al. 2022

INDONES J MED

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Background: Anesthesia procedure is routinely performed for some painful pediatric oncologic procedures such as lumbar puncture (LP) and bone marrow examination (BME). Several studies mentioned that fentanyl and remifentanyl are often used as anesthetic agent of this procedure, but none of them compare the recovery time of both agent. This study aims to compare the recovery time of fentanyl and remifentanyl in pediatric patients undergoing methoterexate therapy. Subjects and Method: This was a double-blind randomized controlled trial on 36 patients who underwent intratechal methotrexate chemoterapy under general anesthesia anesthesia in pediatric intervention room of Moewardi General Hospital Surakarta that met inclusion criteria. The dependent variable was recovery time and the independent variable were fentanyl and remifentanyl. The samples were divided into 2, Fentanyl (F) and Remifentanyl (R) group. Recovery time was recorded after the procedure until the subject reached Pediatric Glasgow Comma Scale (PGCS) of 15. Statistical analysis was Mann Whitney U Test using SPSS 25 for Windows. Results: The mean recovery time of F group was 373.39 ± 29.48 seconds, while R group was 124.67±11.55 seconds. There was a significant difference in recovery time between patients in the Fentanyl group and the Remifentanyl group (p= 0.000). Conclusion: Remifentanyl recovery time was significantly faster than with fentanyl in pediatric patients undergoing intrathecal methotrexate chemotherapy.

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Section: Discussionmentioning

confidence: 99%

Comparison of The Effectiveness of Remifentanyl versus Fentanyl in Pediatric Undergoing Methotrexate Therapy

Purwoko¹,

Putro²,

Pamungkas³

et al. 2022

INDONES J MED

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Repeated Doses of Ketamine Affect the Infant Rat Urogenital System

Kaşıkara¹,

Süngü²,

Arslan³

et al. 2021

DDDT

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Aim Long-term ketamine use is known to create an interstitial cystitis-like problem in the bladder. It is known that long-term intermittent ketamine is applied to the children receiving radiotherapy for sedation. This study was planned to investigate whether this effect seen in the bladder causes similar changes in the kidneys, testicles, epididymis and ductus deferens. Materials and Methods A total of 12 male Wistar Albino rats for 3 weeks were used in the study. Rats were divided equally into 2 groups as, ketamine and saline. 50 mg/kg ketamine was administered intraperitoneally during 21 days to ketamine (K) groups. 1mL/kg saline was administered intraperitoneally during 21 days to saline (S) groups. At the end of 21 days kidney and testicular tissues were taken for biochemical and histopathological evaluations. Results Histological assessment of kidney tissue showed that tubule epithelial congestion increased significantly in the ketamine group. Epididymis congestion and distortion in the epididymal gland were found to be different in the ketamine group when testicular tissue was examined. Thiobarbituric acid reactive substances (TBARS) level in testicular and kidney tissue was found to be significantly higher in the ketamine group according to the saline group. Catalase (CAT) enzyme activity was significantly lower in the ketamine group compared to the saline group in both tissues. Paraoxonase-1 (PON-1) enzyme activity was significantly higher in the ketamine group compared to the saline group. Conclusion We think that the results we have achieved in this study will provide guidance on ketamine, which is repeated in daily anesthesia applications, especially in radiation oncology. But these findings should be supported by clinical and experimental studies that will be conducted in a more detailed and broad series.

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Ketamine–propofol sedation in circumcision

Cited by 2 publications

References 23 publications

Comparison of The Effectiveness of Remifentanyl versus Fentanyl in Pediatric Undergoing Methotrexate Therapy

Comparison of The Effectiveness of Remifentanyl versus Fentanyl in Pediatric Undergoing Methotrexate Therapy

Repeated Doses of Ketamine Affect the Infant Rat Urogenital System

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