2015
DOI: 10.1016/j.bjane.2014.01.006
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Abstract: We found lidocaine to be the most effective analgesic in decreasing propofol related pain. We therefore suggest iv lidocaine for alleviating propofol related pain at operations.

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Cited by 8 publications
(9 citation statements)
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“…The study done by Sing et al 32 on attenuation of pain caused by propfol injection by nitroglycerine, granisetron and magnesium sulfate and showed 36% patients experienced pain in nitroglycerine group. The result of present study is nearly similar to those of studies done by Derakhshan et al, 29 Goktug et al 30 and Sing et al 32…”
Section: Discussionsupporting
confidence: 93%
See 1 more Smart Citation
“…The study done by Sing et al 32 on attenuation of pain caused by propfol injection by nitroglycerine, granisetron and magnesium sulfate and showed 36% patients experienced pain in nitroglycerine group. The result of present study is nearly similar to those of studies done by Derakhshan et al, 29 Goktug et al 30 and Sing et al 32…”
Section: Discussionsupporting
confidence: 93%
“…Their result showed, pain experienced on propofol injection in nitroglycerine group was 36% patients and in placebo group 82% patients. Goktug et al 30 conducted a study titled Lidocaine alleviates propofol related pain much better than metoprolol and nitroglycerine and reported POPI was experienced in 31% patients in nitroglycerine group. Another study done by Jeon Y 31 on propfol injection induced pain with pretreatment by lignocaine and combination of lignocaine and nitroglycerine and showed 43% patients experienced pain in contrast to 7% patients complained pain in combination group.…”
Section: Discussionmentioning
confidence: 99%
“…Lidocaine is not only commonly used to alleviate PIP, but is also used as a comparator when studying 6 a new drug to relieve PIP [2,5,9,11,16,19]. Therefore, we also chose lidocaine as a comparison to study dezocine and chose the doses of lidocaine according to previous studies.…”
Section: Discussionmentioning
confidence: 99%
“…Previous studies have assessed various methods to alleviate PIP, including changing the injection speed, warming up propofol, choosing a large vein and the addition of some drugs [5][6][7][8][9][10][11][12][13]. At present, lidocaine is the most common drug used to relieve PIP.…”
Section: Introductionmentioning
confidence: 99%
“…1 The main adverse reaction experienced by patients upon administration is the sensation of pain which is more pronounced in intravenous injection and ranks seventh among thirty-three major clinical concerns, with an incidence rate between 28% and 90% respectively. 2,3 In the pediatric population the problem of pain has been mitigated to some extent by using a local anesthesia or mixing the drug with lidocaine or by cooling the drug prior to administration. 4 In about 60% of the patients IV injection of 0.5mg/kg lidocaine upon tying a rubber tourniquet on the forearm between 30 seconds to 120 seconds prior to the administration of propofol decreased the pain in 60% of the patients.…”
Section: Introductionmentioning
confidence: 99%