2014
DOI: 10.1016/j.bjane.2013.03.017
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Abstract: Low dose of S-(+)-ketamine administered epidurally had no sympathomimetic effects; it did not change blood pressure, pulse, serum hormones or pulse transit time. Low dose of S-(+)-ketamine administered epidurally did not deepen sympathetic block. Adding 25mg of S-(+)-ketamine to 0.5% bupivacaine does not deprive sympathetic tonus below the level of epidural block at the moment of most expressed sympathetic block and has no effect on sympathetic tonus above the block level.

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Cited by 2 publications
(2 citation statements)
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“…Low dose of S-(+)-ketamine administered epidurally did not deepen sympathetic block. [24] The above studies supports our finding that epidural ketamine is a potent adjuvant to local anesthetics which prolong the duration of analgesia. The present study was undertaken to compare onset of sensory and motor blockade, sedation and hemodynamic profiles of dexmedetomidine with ketamine as an adjuvant to ropivacaine.…”
Section: Discussionsupporting
confidence: 86%
“…Low dose of S-(+)-ketamine administered epidurally did not deepen sympathetic block. [24] The above studies supports our finding that epidural ketamine is a potent adjuvant to local anesthetics which prolong the duration of analgesia. The present study was undertaken to compare onset of sensory and motor blockade, sedation and hemodynamic profiles of dexmedetomidine with ketamine as an adjuvant to ropivacaine.…”
Section: Discussionsupporting
confidence: 86%
“… 10 - 12 Epidural and intravenous administration of ketamine has been shown to reduce postoperative analgesic requirements by 35-40%. 13 - 16 Adding propofol to ketamine reduces the incidence of dose-dependent adverse effects on the cardiovascular and respiratory systems. 10 , 11 …”
Section: Discussionmentioning
confidence: 99%