Efficiency of levobupivacaine and bupivacaine for supraclavicular block: a randomized double-blind comparative study

Ilham, Cenk; Bombacı, Elif; Yurtlu, Serhan; Çolakoğlu, Serhan

doi:10.1016/j.bjane.2013.03.015

Cited by 5 publications

(8 citation statements)

References 6 publications

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“…In the present study, onset of sensory block was 9.33+/-3.27 min in-group B whereas it was 16.13+/-2.83 min ingroup L. This difference was statistically significant (p<0.0001). These findings correlate with the findings of Cenk Ilham, et al [9] The sensory block onset time was 19.64+/-10.70 min in group B and 25.66+/-10.72 min in group L (p<0.036). However Jose Ricardo, et al found that there was earlier sensory block onset with levobupivacaine 0.5% as compared with bupivacaine 0.5% (p<0.05).…”

Section: Section: Anaesthesiasupporting

confidence: 92%

“…Jyoti P Deshpande et al observed that the duration of motor block was more with levobupivacaine (1049.46+/-95.02 min) as compared to bupivacaine (902.37+/-181.46 min) (p = 0.001). [13] Our results matched with the results in the studies done by C.R.Cox et al, [16] Baskan et al, [15] H. Evren et al, [12] Cenk et al, [9] and Dr Charu J Pandya and colleagues, [14] They all found no statistically significant difference between the motor block duration of the two drugs. Moreover, our result showed that sensory block tended to last longer as compared to motor block.…”

Section: Section: Anaesthesiasupporting

confidence: 89%

“…[10] Our findings were consistent with Cenk Ilham et al who found that the motor block onset was statistically faster in group B (5.07+/-4.07 min) than group L (9.2+/-7.9 min). [9] Their findings were statistically significant. Dr Charu J Pandya and colleagues 14 observed that the onset of motor blockade was earlier with bupivacaine as compared to levobupivacaine.…”

Section: Section: Anaesthesiamentioning

confidence: 86%

“…[14] (p<0.05 ). In the studies done by C.R.Cox et al, [16] Baskan et al, [15] H.Evren et al, [12] Cenk et al, [9] they observed no statistically significant difference in the sensory block duration between bupivacaine and levobupivacaine. In the present study, the duration of motor block was similar in both the groups which was statistically insignificant (p=0.779 ); 165.16+/-15.93 min in the bupivacaine group and 164.00+/-16.16 min in the levobupivacaine group.…”

Section: Section: Anaesthesiamentioning

confidence: 95%

“…It was 193.56+/-23.51 in group B and 192.83+/-23.54 in group L. Cenk et al found statistically insignificant difference in the post operative analgesia between the two drugs. [9] Jyoti P Deshpande et al observed that the duration of analgesia was longer with levobupivacaine (1048.32+/-97.24 min) whereas for bupivacaine it was 900.41+/-177.74 min. (p=0.001).…”

Section: Section: Anaesthesiamentioning

confidence: 99%

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Supraclavicular Brachial Plexus Block: A Comparative Clinical Study between Bupivacaine and Levobupivacaine

Jewalikar¹,

Waheed²

2017

AIMDR

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Background: Supraclavicular brachial plexus block is an excellent regional anaesthesia technique for upper extremity surgery. Bupivacaine is most commonly used local anaesthetic in peripheral nerve blocks. The cardiotoxicity of bupivacaine limits its use in large volumes necessitating the need for alternative drugs in upper extremity blocks. Levobupivacaine is a promising drug with less cardiodepressor activity. The basis for this study is to compare its sensory and motor blockade with that of bupivacaine. Methods: This study included 60 ASA grade | and || patients of both sex aged 18 years and above, weighing between 50-70 kg undergoing upper limb orthopaedic surgery. They were randomly allocated to group B (received 30 ml 0.5% bupivacaine) and group L (received 30 ml 0.5% levobupivacaine). Comparison was made regarding onset, duration and quality of sensory and motor blockade between the two groups. Results: Statistically significant difference was found in the onset of sensory and motor blockade between the two drugs with short latency in-group B. Conclusion: Levobupivacaine proves to be a comparable and better alternative to bupivacaine in supraclavicular brachial plexus block owing to its cardiostability.

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Section: Section: Anaesthesiasupporting

confidence: 92%

Section: Section: Anaesthesiasupporting

confidence: 89%

Section: Section: Anaesthesiamentioning

confidence: 86%

Section: Section: Anaesthesiamentioning

confidence: 95%

Section: Section: Anaesthesiamentioning

confidence: 99%

See 3 more Smart Citations

Supraclavicular Brachial Plexus Block: A Comparative Clinical Study between Bupivacaine and Levobupivacaine

Jewalikar¹,

Waheed²

2017

AIMDR

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Comparison of duration of analgesic effect of nalbuphine and morphine as an adjuvant to bupivacaine in the supraclavicular block under ultrasound guidance

et al. 2020

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Background: Although many studies are available in the literature that has analyzed the effects of morphine, nalbuphine, and other opioids, no study had compared the effects of nalbuphine versus morphine as an adjuvant to bupivacaine in the supraclavicular block under the guidance of ultrasound. Methodology: A randomized, double-blinded, prospective study was carried out on 60 patients of the American Society of Anesthesiologists Class I and II who were undergoing upper limb surgeries under the supraclavicular block. Patients were randomly allocated into two groups ( n = 30). Group N received 20 ml of 0.5% bupivacaine with 50 μg.kg −1 of nalbuphine, while Group M received 20 ml of 0.5% bupivacaine with 50 μg.kg −1 of morphine. The characteristics of sensory and motor blocks, hemodynamic changes, duration of analgesia, adverse effects, and analgesic requirements were studied at different time intervals. Results: In Group N, there was a statistically significant reduction in the time of onset of sensory block (9.9 ± 3.0 vs. 12.2 ± 2.6 min, P = 0.002) and motor block (14.4 ± 3.6 vs. 19.4 ± 3.6 min, P = 0.0005). The duration of sensory and motor blockade and duration of analgesia were comparable. There was no statistically significant difference regarding block characteristics and hemodynamic parameters. Conclusion: Nalbuphine when added to bupivacaine as an adjuvant had significantly shortened the time of onset of sensory and motor blockade than morphine. However, the duration of analgesia, sensory and motor blockade of nalbuphine versus morphine were comparable.

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Comparison of Ropivacaine and Levobupivacaine in Supraclavicular Brachial Plexus Blocks-A Double Blinded Randomized Control Study

Thalamati¹,

Sambandam²,

V³

et al. 2021

Turk J Anaesthesiol Reanim

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Efficiency of levobupivacaine and bupivacaine for supraclavicular block: a randomized double-blind comparative study

Abstract: 30 ml 0.5% bupivacaine and levobupivacaine provide similar block characteristics for supraclavicular block. Bupivacaine leads to faster motor and sensory block onset compared to levobupivacaine however similar duration of postoperative analgesia.

Cited by 5 publications

References 6 publications

Supraclavicular Brachial Plexus Block: A Comparative Clinical Study between Bupivacaine and Levobupivacaine

Supraclavicular Brachial Plexus Block: A Comparative Clinical Study between Bupivacaine and Levobupivacaine

Comparison of duration of analgesic effect of nalbuphine and morphine as an adjuvant to bupivacaine in the supraclavicular block under ultrasound guidance

Comparison of Ropivacaine and Levobupivacaine in Supraclavicular Brachial Plexus Blocks-A Double Blinded Randomized Control Study

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