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Cited by 4 publications
(6 citation statements)
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“…[7][8][9] There are 15 previous reports of the use of TNF-a inhibitors for NL, with only 1 report of PNL responding to adalimumab. 1,6,10 Our patient was transitioned to adalimumab 40 mg subcutaneous every other week and demonstrated marked improvement. Because of medication coverage, she was switched to infliximab-abda 5 mg/kg at 8 weeks intervals.…”
Section: Diagnosismentioning
confidence: 90%
See 3 more Smart Citations
“…[7][8][9] There are 15 previous reports of the use of TNF-a inhibitors for NL, with only 1 report of PNL responding to adalimumab. 1,6,10 Our patient was transitioned to adalimumab 40 mg subcutaneous every other week and demonstrated marked improvement. Because of medication coverage, she was switched to infliximab-abda 5 mg/kg at 8 weeks intervals.…”
Section: Diagnosismentioning
confidence: 90%
“…3 There are only 22 previously reported cases of PNL; however, ;90% of cases are associated with DM. [3][4][5][6] Although granuloma annulare (GA), sarcoidosis, and rheumatoid nodules can present generalized with focal ulceration and perforation, histopathologic morphology is valuable in differentiation. Nodular granulomatous infiltrates with a paucity of inflammatory cells characterizes sarcoidosis, whereas dermal deposits of amorphous eosinophilic material surrounded by palisading granulomatous infiltrate are seen in rheumatoid nodules.…”
Section: Diagnosismentioning
confidence: 99%
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“…1,2 En 1977 Parra y colaboradores 3 reportaron los primeros casos de necrobiosis lipoídica perforante en tres pacientes con múltiples «tapones» queratósicos dispersos irregularmente sobre la superficie de las lesiones, los que al desprenderse originan depresiones similares a cráteres erosivos. 4 En 2017 Kluger y colaboradores 5 reportaron el caso de un hombre de 43 años de edad, portador de diabetes mellitus, quien desarrolló NL en miembros inferiores, la cual se manifestaba con lesiones queratósicas, cuya histopatología era sugestiva de enfermedad por eliminación transepidérmica.…”
Section: Introductionunclassified