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Cited by 1,257 publications
(661 citation statements)
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References 103 publications
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“…It is recognized by distinct morphological changes, including cell shrinkage, nuclear condensation and fragmentation [3]. It has been proposed that all cells except blastomeres would die by apoptosis in the absence of survival signals [4].…”
Section: Introductionmentioning
confidence: 99%
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“…It is recognized by distinct morphological changes, including cell shrinkage, nuclear condensation and fragmentation [3]. It has been proposed that all cells except blastomeres would die by apoptosis in the absence of survival signals [4].…”
Section: Introductionmentioning
confidence: 99%
“…It has been proposed that all cells except blastomeres would die by apoptosis in the absence of survival signals [4]. The ability of cells to undergo apoptosis can be induced by diverse stimuli including chemicals, radiation and viruses [3,5]. These diverse stimuli trigger a range of different signalling events, including elevations in cytosolic Ca 2÷, cAMP accumulation, alterations in protein kinase C and tyrosine kinase activities, oxidative stress, generation ofceramide or nitric oxide [6].…”
Section: Introductionmentioning
confidence: 99%
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“…This represents the physiologically relevant mode of cell death that proceeds via an energy-dependent cascade of biochemical and morphological changes which result in the death and elimination of the cell. 1 In the normal prostate, the rate of cell proliferation is balanced by an equal rate of cell death, so homeostasis of the gland is maintained. 1 In both clinical conditions associated with the pathogenesis of prostatic disease in the aging male, prostate cancer and benign prostate hypertrophy (BPH), there is an imbalance in the growth equation in favour of cell proliferation, thus resulting in an increased cell number and abnormal prostatic growth.…”
mentioning
confidence: 99%
“…Apoptosis is characterized by loss of cell function and decrease in cell size and its morphology. 19 Zagariya et al 8 showed apoptosis in the airway epithelium 8 h after meconium instillation using ISEL-DNA end labeling. The apoptosis reported from an earlier study coincide with an increase in the production of NO in this study up to 8 h. This might play a crucial role in meconium-induced apoptosis.…”
Section: Results and Analysismentioning
confidence: 99%