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Cited by 12 publications
(4 citation statements)
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References 31 publications
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“…De la Maza and Parra studied equimolar mixtures of Triton and SDS and found values of R e sat = 0.87 and R e (50% dequenching) = 0.19, which are just average values between those for Triton and SDS alone and which are virtually constant at C L = 1−5 mM as indicated by linear relationships between [ C 1 + C 2 ]* and C L . This is in line with our model but represents the special case that the (apparent) partition coefficients of both surfactants are virtually identical (∼4 mM −1 , converted to the definition used here).…”
Section: Discussionmentioning
confidence: 94%
See 1 more Smart Citation
“…De la Maza and Parra studied equimolar mixtures of Triton and SDS and found values of R e sat = 0.87 and R e (50% dequenching) = 0.19, which are just average values between those for Triton and SDS alone and which are virtually constant at C L = 1−5 mM as indicated by linear relationships between [ C 1 + C 2 ]* and C L . This is in line with our model but represents the special case that the (apparent) partition coefficients of both surfactants are virtually identical (∼4 mM −1 , converted to the definition used here).…”
Section: Discussionmentioning
confidence: 94%
“…Our model applies to additive, solute-induced effects that occur at a specific solute-to-lipid mole ratio in the membrane, R e , regardless of the aqueous concentration of the solute. Potential examples are a characteristic membrane leakage, a specific degree of membrane disordering and curvature strain as recognized by a spectroscopic signal , or in terms of a certain excess enthalpy, , or membrane saturation by a surfactant, inducing the onset of membrane lysis or solubilization to micelles. Analogously, the model applies to micelles and predicts, for example, the minimum surfactant content in micelles denoted by the mole ratio R e sol (corresponds to R e at the completion of membrane solubilization) or the lipid-induced sphere-to-rod transition. By assigning an effective lipid concentration to a cell suspension, the model could also become applicable to the threshold solute concentration for inducing fast lipid flip-flop in erythrocytes, hemolysis, or minimum inhibitory concentrations of drugs and biomolecules on cells.…”
Section: Introductionmentioning
confidence: 99%
“…Triton X-100 solubilization of phosphatidylcholine vesicles have already been quite extensively studied. , The solubilization process is proposed to follow the three-stage model . In this study we have compare the penetration of Triton X-100 into sphingomyelin and phosphatidylcholine bilayers and examined the onset of solubilization in the two phospholipid membrane types.…”
Section: Discussionmentioning
confidence: 99%
“…Thereafter the fluorescence of the filtrate could be examined. To estimate the total amount of entrapped ethidium bromide, 11,11-[Ru2(phen)4BD]Cl4, dextran and PNA, a small amount of liposome solution was withdrawn and solubilized with Triton X-1 00 (final concentration 2% v/v), and the fluorescence was measured (16). The fluorescence experiments were carried out using an Aminco spectrofluorimeter for ethidium bromide (Aex=490nm, Aem=590nm), 11,11-[Ru 2 (phen) 4 BD]Cl 4 (Aex=440nm, Aem=615nm) and dextran samples (Aex=485nm, Aem=518nm), and the PNA efflux rates were determined using a SPEX 't2 spectrofluorimeter (Aex=490nm, Aem=5 I 8nm).…”
Section: Methodsmentioning
confidence: 99%