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citations
Cited by 460 publications
(260 citation statements)
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References 21 publications
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“…In fact, 21 of 32 patients who experienced CHF had a reduction Ͻ 30% in LVEF values from baseline values, which Schwartz et al considered the cut-off level for increased risk of CHF. 7 Furthermore, in our study, similar LVEF changes occurred in many other patients who did not develop CHF. Thus, further investigation will be required to help predict whether a patient is at high risk for CHF.…”
Section: Discussionsupporting
confidence: 84%
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“…In fact, 21 of 32 patients who experienced CHF had a reduction Ͻ 30% in LVEF values from baseline values, which Schwartz et al considered the cut-off level for increased risk of CHF. 7 Furthermore, in our study, similar LVEF changes occurred in many other patients who did not develop CHF. Thus, further investigation will be required to help predict whether a patient is at high risk for CHF.…”
Section: Discussionsupporting
confidence: 84%
“…LVEF was measured by MUGA, which reportedly is a good predictor of CHF. 7 Therefore, we believed that we would be able to predict which individuals would be at risk of developing CHF through careful monitoring. However, the data presented in the current report indicate that LVEF may not be an accurate predictor of CHF.…”
Section: Discussionmentioning
confidence: 99%
“…by risk factors, pose a risk of premature discontinuation of effective anthracycline therapy. On the other hand, because of a wide individual variability in toxic anthracycline doses (von Hoff et al, 1979;Schwartz et al, 1987), cardiotoxicity may occur at unexpectedly low cumulative doses. Serial assessment of LVEF by RVG has been the most commonly used method of cardiac monitoring.…”
Section: Discussionmentioning
confidence: 99%
“…If the LVEF decreased more than 10% units or was 550%, the RVG scan was repeated before the subsequent CHOP course. A decrease of LVEF 410% units to an final LVEF 450% was used as a cut-off point in the analyses as indicative of doxorubicin-induced cardiotoxicity (CT) (Schwartz et al, 1987).…”
Section: Radionuclide Ventriculographymentioning
confidence: 99%
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