2020
DOI: 10.1007/s40898-020-00009-x
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Abstract: Carbon nanotubes (CNTs), with unique graphitic structure, superior mechanical, electrical, optical and biological properties, has attracted more and more interests in biomedical applications, including gene/drug delivery, bioimaging, biosensor and tissue engineering. In this review, we focus on the role of CNTs and their polymeric composites in tissue engineering applications, with emphasis on their usages in the nerve, cardiac and bone tissue regenerations. The intrinsic natures of CNTs including their physic… Show more

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Cited by 55 publications
(29 citation statements)
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References 211 publications
(243 reference statements)
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“… 31 Furthermore, the introduction of carbonaceous nanofillers into neural biomaterials is questionable because of possible cytotoxic effects. 32 , 33 …”
Section: Introductionmentioning
confidence: 99%
“… 31 Furthermore, the introduction of carbonaceous nanofillers into neural biomaterials is questionable because of possible cytotoxic effects. 32 , 33 …”
Section: Introductionmentioning
confidence: 99%
“…If CNTs are incorporated into composite materials for medical applications, evidence of their bioactivity and toxicity is essential. The presence of CNTs in the composite may have no detrimental effects and could even enhance its bioactive properties [21][22][23][24][25][26][27][28][29][30][31][32][33][34][35][36][37]. A study by Georg et al [38] tested the response of MWCNTs to human lung epithelial cells, osteoblast-like cells and primary osteoblast cells.…”
Section: Introductionmentioning
confidence: 99%
“…In fact, the main advantage of the non-covalent functionalization is that the carbon atoms in the nanotubes keep their sp 2 hybridization and the electrical properties of CNTs remain undamaged. 26,97,137 In addition to the direct immobilization described above, indirect immobilization through the use of binding bio-molecules attached to the CNTs (with both covalent and non-covalent bonds) facilitates the subsequent immobilization of the bio-recognition elements. Using binding molecules [such as innovative functionalization approach based on the modification of t h eP Is ub s t r a t es u r f a c eb e l o wt h es e m i c o n d u c t i n gC N T sc h a n n e l .…”
Section: A Functionalization Methodsmentioning
confidence: 99%