Effect of sulfonamide antibiotics on microbial diversity and activity in a Californian Mollic Haploxeralf

Gutiérrez, I; Watanabe, Naoko; Harter, Thomas; Glaser, Bruno; Radke, Michael

doi:10.1007/s11368-009-0168-8

Cited by 81 publications

(35 citation statements)

References 26 publications

(28 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Higher elimination half-life of sulphadimidine in starved turkeys may also pose risk of environmental contamination, especially when droppings from turkeys administered sulphadimidine is used as organic manure. Watanabe et al (2010) reported that sulphadimidine concentration of ground water was 0.6 ng/l. Sulphadimidine in manure and soil may affect soil microbial and enzyme activities (Caracciolo et al, 2015).…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Tissue distribution of sulphadimidine sodium in non-starved and starved grower turkeys (meleagris gallopavo)

Agbo

Saganuwan

Azubuike

2016

IJPT

View full text Add to dashboard Cite

Background: The use of veterinary drugs in food-producing animals has potential to generate residues in edible tissues and posses health hazard to consumers especially when the withdrawal period is not observed. Objectives: The study was conducted to determine the tissue residue and withdrawal period of sulphadimidine in non-starved and starved grower turkeys following a single intramuscular administration. Methods: Forty two turkeys of both sexes and 12 weeks old weighing 1.57±0.2 kg were divided into two groups of twenty one each. One group was administered a single intramuscular dose of sulphadimidine sodium (100mg/kg body weight). The other group was kept off-feed for 48 hours before drug administration. Three turkeys each were sacrificed from the starved and non-starved group and two grammes (2g) of tissue sample were harvested from selected tissues. Results:The results showed that the drug residues persisted in all the tissues of turkeys sampled for up to thirty (30) days after drug administration. The starved turkeys maintained consistently higher concentrations of the drug in the tissues than fed ones. Sulphadimidine residue was significantly increased (p<0.05) between days 3 to 6 in the spleen of non-starved turkeys. However, the concentrations in the spleen decreased significantly (p<0.05) between days 6 to 10 and 25 to 30. Conclusion: Sulphadimidine residue persisted in the tissues of non-starved and starved turkeys for up to 30 days after intramuscular injection. This should be given due consideration in the estimation of the withdrawal period for the drug, since sulphadimidine residue in meat > 0.2 ppm is unsafe for human consumption.

show abstract

Section: Discussionmentioning

confidence: 99%

“…Sulphadimidine affects both the functioning (i.e. enzymatic activities) and the structural diversity of a soil microbial community at relatively low antimicrobial concentration, 1-900µg/g (Gutierrez et al, 2010). This signifies that sulphadimidine is a persistent organic pollutant due to its resistance to biological decomposition.…”

Section: Discussionmentioning

confidence: 99%

Tissue distribution of sulphadimidine sodium in non-starved and starved grower turkeys (meleagris gallopavo)

Agbo

Saganuwan

Azubuike

2016

IJPT

View full text Add to dashboard Cite

show abstract

“…While results from these and other studies suggest a low risk for exposure to pathogens (Brooks et al .. 2005: Tanner et al, 2005, significant knowledge gaps s till exist with respect to the fate and transport of bioaerosols, making it difficult to predicate the health risks associated with aerosolized pathogens accurately (Pillai and Ricke. 2002 Gutierrez et al .. 2010: Toth et al, 2011. In contrast.…”

Section: Aerosolization Of Pathogensmentioning

confidence: 99%

Sustainable manure management.

Leytem¹,

Dungan²,

Kleinman³

2013

Sustainable Animal Agriculture

View full text Add to dashboard Cite

show abstract

“…In the United States, 80% of antibiotics are used in livestock production, representing approximately 15-million kg of antibiotics annually (Lipsitch et al 2002;FDA 2013); globally livestock antibiotic use is projected to increase by 67% between 2010 and 2030 (Van Boeckel et al 2015). After dosing, 40-90% of antibiotics are excreted by livestock either intact or as a biologically active metabolite (Sarmah et al 2006;Guti errez et al 2010;Toth et al 2011). Livestock manure either collects in pastures or is applied to cultivated fields as fertiliser, therefore potentially contributing up to 13-million kg of antibiotics to the environment annually (Sarmah et al 2006;FDA 2013).…”

Section: Introductionmentioning

confidence: 99%

Prolonged exposure to manure from livestock‐administered antibiotics decreases ecosystem carbon‐use efficiency and alters nitrogen cycling

et al. 2019

View full text Add to dashboard Cite

Microbial communities drive soil ecosystem function but are also susceptible to environmental disturbances. We investigated whether exposure to manure sourced from cattle either administered or not administered antibiotics affected microbially mediated terrestrial ecosystem function. We quantified changes in microbial community composition via amplicon sequencing, and terrestrial elemental cycling via a stable isotope pulse‐chase. Exposure to manure from antibiotic‐treated cattle caused: (i) changes in microbial community structure; and (ii) alterations in elemental cycling throughout the terrestrial system. This exposure caused changes in fungal : bacterial ratios, as well as changes in bacterial community structure. Additionally, exposure to manure from cattle treated with pirlimycin resulted in an approximate two‐fold increase in ecosystem respiration of recently fixed‐carbon, and a greater proportion of recently added nitrogen in plant and soil pools compared to the control manure. Manure from antibiotic‐treated cattle therefore affects terrestrial ecosystem function via the soil microbiome, causing decreased ecosystem carbon use efficiency, and altered nitrogen cycling.

show abstract

Effect of sulfonamide antibiotics on microbial diversity and activity in a Californian Mollic Haploxeralf

Cited by 81 publications

References 26 publications

Tissue distribution of sulphadimidine sodium in non-starved and starved grower turkeys (meleagris gallopavo)

Tissue distribution of sulphadimidine sodium in non-starved and starved grower turkeys (meleagris gallopavo)

Sustainable manure management.

Prolonged exposure to manure from livestock‐administered antibiotics decreases ecosystem carbon‐use efficiency and alters nitrogen cycling

Contact Info

Product

Resources

About