2017
DOI: 10.1007/s10856-016-5828-9
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Abstract: Duraplasty is necessary in nearly 30% of all neurological surgeries. Different tissues and materials have been evaluated in dura mater repair or as dural substitutes in neurosurgery. The aim was to evaluate the biocompatibility of the bacterial cellulose (BC) membranes, produced from sugarcane molasses, for dural defect repair in rats. Forty adults males Wistar rats divided into two groups: a control (ePTFE) and an experimental (BC). Bilateral frontoparietal craniectomy was performed, and a dural defect was cr… Show more

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Cited by 30 publications
(20 citation statements)
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“…Other studies highlight the potential of BNC as substrate for in vitro models 25 and as a drug delivery matrix. 26,27 Despite these promising reports, the capability of BNC to heal other body surfaces such as the cornea or the dura mater 28 remain largely unexploited. 29 Therefore, based on the outstanding performance of BNC on skin wound healing, we hypothesize that BNC also holds potential as an ocular surface bandage.…”
Section: Introductionmentioning
confidence: 99%
“…Other studies highlight the potential of BNC as substrate for in vitro models 25 and as a drug delivery matrix. 26,27 Despite these promising reports, the capability of BNC to heal other body surfaces such as the cornea or the dura mater 28 remain largely unexploited. 29 Therefore, based on the outstanding performance of BNC on skin wound healing, we hypothesize that BNC also holds potential as an ocular surface bandage.…”
Section: Introductionmentioning
confidence: 99%
“…Duraplasty is required in nearly 30% of all neurological surgeries. Several scaffolds and tissues were assessed to repair dura mater or as dural substitutes (Lima et al 2017). Bacterial cellulose is as a biodegradable, biocompatible natural polymer, with a high mechanical strength and the potential to meet the characteristics of an ideal dura mater membrane.…”
Section: Soft Tissue Engineeringmentioning
confidence: 99%
“…In veterinary medicine, studies report that bacterial cellulose (BC) was used in the bioengineering of hard (Saska et al 2011;Yoshino et al 2013), fibrocartilaginous (Tanaka et al 2014) and soft tissue engineering (Bodin et al 2010;Lima et al 2017). Bacterial cellulose is a polysaccharide used as scaffold in various medical fields (Rajwade et al 2015).…”
mentioning
confidence: 99%
“…Manual addition of hydrogen bonding molecules to the culture media can control Iα/Iβ ratios and molecular weights in resulting cellulose particles (18,19). BC crystals interweave in random patterns according to bacterial movement and form a pellicle at the oxygen-media interface that grows to take the shape of the bioreactor.…”
Section: Synthetic Biology Strategies For Polysaccharide Biosynthesismentioning
confidence: 99%