2013
DOI: 10.1007/s10695-013-9797-3
|View full text |Cite
|
Sign up to set email alerts
|

Abstract: The extensive use of pharmaceuticals in human and veterinary medicine may enter the aquatic environment and pose a serious threat to non-target aquatic organisms like fish. In this study, Indian major carp Cirrhinus mrigala was exposed to different concentrations (1, 10 and 100 μg L⁻¹) of most commonly used pharmaceutical drugs clofibric acid (CA) and diclofenac (DCF) to evaluate its impacts on certain enzymological parameters during short- and long-term exposures. During short-term (96 h) exposure period, pla… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
1
1
1

Citation Types

0
3
0

Year Published

2015
2015
2021
2021

Publication Types

Select...
7
1

Relationship

0
8

Authors

Journals

citations
Cited by 14 publications
(3 citation statements)
references
References 43 publications
0
3
0
Order By: Relevance
“…The GOT and GPT activities in the stress conditions of animals could cause the impairment of muscle and liver cells [74]. Li et al [75] suggested that the organism increased the metabolic rate to mitigate the stress condition.…”
Section: Plasma Enzymes Activitymentioning
confidence: 99%
“…The GOT and GPT activities in the stress conditions of animals could cause the impairment of muscle and liver cells [74]. Li et al [75] suggested that the organism increased the metabolic rate to mitigate the stress condition.…”
Section: Plasma Enzymes Activitymentioning
confidence: 99%
“…In the literature, many works use the zebrafish model to study the potential of different drugs on humans [97] and to evaluate the toxicological effects of several type of pollutants on zebrafish [107], but no studies focused on the effects of human drugs released in the aquatic system on adult zebrafish at the biochemical level, which is the purpose of this review. Moreover, among the environmental biomarkers used to study and monitor pollution levels, biochemical responses (with ecologically meaning endpoints) are among the most important for assessing the risks and quality of an aquatic system [108], being that they provide information on the health of individual organisms and, therefore, ecosystems [109]. In the future, this could help with the design of experiments aimed to increase the knowledge of the effects of drugs, both generally and at particular concentrations, leading to the development and improvement of regulations for environmental monitoring.…”
Section: Danio Rerio As a Model Organismmentioning
confidence: 99%
“…That is, the NEC component has no contribution to CI of a mixture Yu et al, 2014). Moreover, it was shown that some chemicals such as pesticides and antibiotics may exhibit different toxicities in different exposure times (Bao et al, 2013;Saravanan et al, 2013). Zhu et al (2009c) found that one insecticide (dipterex) and two antibiotics (chloramphenicol and tetracycline hydrochloride) have distinct different toxicities between the short-term (15 min) and long-term (12 h) tests, while the other two antibiotics (streptomycin sulfate and paromomycin) only have the long-term toxicities.…”
Section: Introductionmentioning
confidence: 99%