2009
DOI: 10.1007/s00264-009-0853-7
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Abstract: Paget's disease of bone (PDB) is a localised chronic osteopathy leading to bone deformities, bone hypervascularity, structural weakness and altered joint biomechanics. The pelvis and upper femur are frequently involved, resulting in disabling hip disease, and total hip arthroplasty (THA) may be required. We performed a retrospective study on the management and the outcome of 39 uncemented hydroxyapatite fully-coated THA in patients with PDB of the hip. The follow-up averaged 79.4 months (range 24-194). Functio… Show more

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Cited by 33 publications
(35 citation statements)
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“…The reported post-operative improvement in functional outcome and patient satisfaction is significant in all studies in this review, and is largely comparable to the outcome of THA in other patients[17]. The overall revision rate was 8% at 7 years with aseptic loosening being the main reason for revision (70%).…”
Section: Discussionsupporting
confidence: 64%
“…The reported post-operative improvement in functional outcome and patient satisfaction is significant in all studies in this review, and is largely comparable to the outcome of THA in other patients[17]. The overall revision rate was 8% at 7 years with aseptic loosening being the main reason for revision (70%).…”
Section: Discussionsupporting
confidence: 64%
“…Another consideration is whether to use cemented or uncemented components; in the hip arthroplasty literature, this issue is controversial. 8,9,12,17,18,22,25,28,35 Based on our experience, we recommend cemented humeral components, as a cemented component allows for improved fixation in a potentially voluminous and pathologic humeral intramedullary canal. The final consideration is whether or not to use prophylaxis for heterotopic ossification.…”
Section: Discussionmentioning
confidence: 98%
“…By treating patients with bisphosphonates until laboratory values have normalized, a surgeon can minimize the risk for excessive intraoperative blood loss. [10][11][12]25,32,35 There are also specific technical measures that must be taken intraoperatively to optimize outcomes and minimize complications when performing an arthroplasty in patients with Paget's Disease. 28 First of all, the treating surgeon must be prepared for the potential for excessive blood loss.…”
Section: Discussionmentioning
confidence: 99%
“…Although there was initial apprehension on the use of cementless prostheses in rheumatoid arthritis patients due to a perceived high rate of mechanical failure in these patients, recent evidence suggests that there was no significant difference in the overall outcomes between cemented and cementless prostheses in rheumatoid patients 41 . Other workers have also recently shown very good medium term outcomes of cementless THAs in a cohort of patients with Paget's disease; with 84% of these patients having excellent outcomes after 79.4 months of follow-up 42 .…”
Section: Un-cemented (Cementless) Thasmentioning
confidence: 98%