2000
DOI: 10.1002/etc.5620190521
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Abstract: Kowledge is limited regarding methylsulfone (MeSO2)‐polychlorinated biphenyl (PCB), and especially MeSO2–2,2‐bis(chlorophenyl)‐1,1‐dichloroethylene (DDE), metabolites in cetacean species. We hypothesized that the ability of beluga whale (Delphinapterus leucas) to biotransform PCB and DDE compounds, and to form and degrade their MeSO2 PCB and ‐DDE metabolites, is related to the capacity for xenobiotic metabolism. Adipose biopsies were collected from male and female beluga whale from distinct populations in the … Show more

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Cited by 8 publications
(1 citation statement)
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“…In addition, hydroxyl (OH) and persistent methyl sulfone (MeSO 2 ) PCB metabolite residues have been determined in several marine mammals (e.g., seals). These metabolites are a direct indication of active metabolism of selected PCB congeners in these species [23][24][25][26]. Neither the observed changes in residue patterns of PCBs in tissues nor the presence of their metabolites directly specifies which CYPs are involved in the metabolism of PCBs in marine mammals.…”
Section: Introductionmentioning
confidence: 99%
“…In addition, hydroxyl (OH) and persistent methyl sulfone (MeSO 2 ) PCB metabolite residues have been determined in several marine mammals (e.g., seals). These metabolites are a direct indication of active metabolism of selected PCB congeners in these species [23][24][25][26]. Neither the observed changes in residue patterns of PCBs in tissues nor the presence of their metabolites directly specifies which CYPs are involved in the metabolism of PCBs in marine mammals.…”
Section: Introductionmentioning
confidence: 99%