1986
DOI: 10.1002/ana.410200116
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Abstract: Acute infection with Coxiella burnetii usually results in a self-limited illness, but it can occasionally cause chronic endocarditis or hepatitis. Headache is a common presenting symptom of acute infection with this agent, but specific neurological abnormalities are rare. We report the case of a patient with acute Q fever that caused frank encephalitis. We also review the literature on central nervous system disease attributable to C. burnetii.

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Cited by 22 publications
(10 citation statements)
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“…Laboratory Findings The white blood cell count ranged from 2.5 to 15.8X107L (mean, 5.8X10VL; median, 5.0X10VL). It was lower than 5.0X109/L in six patients, 15.8X109/L in one, and ranged between 5.0 and 10.0X109/L in the remainder.…”
Section: Clinical Manifestationsmentioning
confidence: 99%
See 1 more Smart Citation
“…Laboratory Findings The white blood cell count ranged from 2.5 to 15.8X107L (mean, 5.8X10VL; median, 5.0X10VL). It was lower than 5.0X109/L in six patients, 15.8X109/L in one, and ranged between 5.0 and 10.0X109/L in the remainder.…”
Section: Clinical Manifestationsmentioning
confidence: 99%
“…[15][16] Most patients with noncomplicated Q fever have a nor¬ mal white blood cell count, but in some cases, leukocyto¬ sis or leukopenia may be found.6,7 The differential count may reveal an increase of the immature forms.6·7 The platelet count may be moderately decreased in some patients.7 The erythrocyte sedimentation rate is usually normal or slightly increased.7 Other neurologic pictures, such as encephalitis, confusional states, and extrapyramidal signs, have been rarely described.…”
Section: Clinical Manifestationsmentioning
confidence: 99%
“…Our first patient had persistent vague neurologic complaints after being treated for acute Q-fever meningoencephalitis. Neurologic manifestations of acute Q fever are uncommon but date back to World War II and may include primary infection (meningitis and encephalitis) and symptoms as a result of embolic phenomena secondary to Q-fever endocarditis [30][31][32]. Signs and symptoms vary and can include extrapyramidal symptoms, aphasia, ataxia, weakness, seizures, decreased visual acuity, diplopia, disorientation, hallucinations, and behavioral disturbances [27,32].…”
Section: Discussionmentioning
confidence: 98%
“…Schuil and colleagues [34] ascribed bilateral optic neuritis with lasting unilateral blindness in a 59-year-old farmer to Q fever. Brooks and colleagues [35] recounted the case of a 34-year-old man who developed an acute encephalitis 6 weeks after an attack of Q fever which relapsed but subsequently responded to a course of doxycycline. Shaked and colleague [36] described a female soldier with meningoencephalitis, bilateral optic neuritis and abducens nerve paralysis; CSF showed a lymphocytosis and increased protein.…”
Section: Clinical Featuresmentioning
confidence: 99%