0582: Discordance between mitral valve area and mean transmitral pressure gradient in mitral stenosis: is mean gradient marker of the severity or parameter of tolerance in severe mitral stenosis?

Prognostic contribution of two-dimensional left atrial strain in patients with asymptomatic mitral stenosis in the Tunisian population

“…From the ROC curves cut-offs, we determined that when Left Atrium Area (LAA) was larger than 30 cm2 and left atrium volume (LAV) more than 100ml/m2, the risk of occurrence of an event increased significantly respectively (LAA: 69% vs 10%; p = 0.01; OR = 6.6; 95% CI [1.5-28]) and (LAV: 71.4% vs 39%; p = 0.002; OR = 4; 95% CI [1. [1][2][3][4][5][6][7][8][9][10][11][12][13]). We have demonstrated from the ROC (Fig 1) curves cut-offs that it was the same for left atrium deformation parameters, both Peak Atrial Longitudinal Strain (PALS) <25% and Peak Atrial Contraction Strain (PACS) <10 % were predictive of events in a univariate study with the following respective odds ratios (ORs) (PALS: 83% vs 30.4%; p = 0.0001; OR = 11.4; 95% CI ), and (PACS: 90% vs 47%; p = 0.001; OR = 9.8; 95% CI [2.3-41]) (see Table 3).…”

“…Prvobitno je odabrano 80 pacijenata, ali je samo 53 praćeno, a zatim podeljeno u dve grupe: 30 pacijenata je imalo najmanje jedan od navedenih ishoda, a 23 pacijenta nisu imala nijedan od ishoda u skladu sa glavnim kriterijumima studije. U univarijantnoj analizi i za konvencionalne ehokardiografske parametre utvrdili smo da ako je površina leve pretkomore (LAA) veća od 30 cm 2 i zapremina leve pretkomora (LAV) veća od 100 ml/m 2 , rizik od pojave nekog od ishoda značajno se povećava (LAA: 69% naspram 10%; p = 0,01; OR = 6,6; 95% CI [1,) i (LAV: 71,4% naspram 39%; p = 0,002; OR = 4; 95% CI [1,[1][2][3][4][5][6][7][8][9][10][11][12][13]). Isto, za parametre deformacije leve pretkomore i maksimum longitudinalnog pretkomornog opterećenja (PALS) < 25% i maksimum pretkomornog kontrakcionog opterećenja (PACS) < 10% predviđalo je pojavu nekog od ishoda u univarijantnoj studiji sa sledećim odnosima šansi (OR) (PALS: 83% naspram 30,4%; p = 0,0001; OR = 11,4; 95% CI ) i (PACS: 90 % vs 47%; p = 0,001; OR = 9,8; 95% CI [2,).…”

“…Rheumatic mitral stenosis (MS) is a frequent acquired valve pathology in our country and in developing countries (1). Speckle Tracking is an ultrasound technique that is particularly effective in terms of spatial and temporal resolution.…”