influence of organotin compounds on the reaction rate depends on the nature of organic group and, in the case of butyl and methyl derivatives, on the quantity of these groups. The influence of addition of the extremely toxic methylmercury salts on the decomposition rate of hydrogen peroxide does not differ from the influence of inorganic mercury salts. The decrease of the H 2 O 2 decomposition rate in the presence of tin and mercury compounds may be connected with inhibition of catalase enzyme. At these conditions, an excess of hydrogen peroxide is formed, what brings to the change of permeability of biomembranes and oxidative stress. When (HO 3 S) 4 TPPН 2 is added in erythrocytes hemolysate the rate of enzymatic reaction is similar to control one. So an inclusion of sulfo group on the periphery of porphyrin molecule TPPH 2
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